VALVULAR HEART DISEASE. Learning objectives. Describe the etiology and clinical symptoms of acute rheumatic fever. Describe the pathology and natural history of acute rheumatic fever and rheumatic heart disease. Describe an Aschoff body.
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ACUTE RH. FEVER-- Pancarditis
Aschoff/ Anitschow cells
Aschoff giant cell
rheumatic aortic stenosis
With fused commisures
rheumatic mitral valve,
The major clinical manifestations of ARF:
Minor manifestations of ARF:
Valvular disease and its sequelae (yrs later)
Most cases are bacterial although chlamydiae and ricketia also implicated