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Ratio Impact on Donor Chimerism in Mx1-Cre.Survivin.fl/fl Mice Post-Transplantation Study

This study explores the effect of varying donor-competitor ratios on donor chimerism in Mx1-Cre.Survivin.fl/fl mice after transplantation across different time points. Results indicate a significant correlation between the ratios and donor chimerism levels.

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Ratio Impact on Donor Chimerism in Mx1-Cre.Survivin.fl/fl Mice Post-Transplantation Study

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  1. Supplementary Figure 1 B A Donor : Competitor = 2:1 Donor : Competitor = 0.5:1 75 Mx1-Cre Survivin fl/fl 75 Survivin fl/fl 50 * * * 50 % donor chimerism (CD45.2) % donor chimerism (CD45.2) * * Mx1-Cre Survivin fl/fl * * 25 Survivin fl/fl 25 * 4 8 12 16 20 4 8 12 16 20 weeks after transplantation weeks after transplantation

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