slide1 n.
Download
Skip this Video
Download Presentation
The diamond concept for the treatment of long bone non- unuions and Bone defects .

Loading in 2 Seconds...

play fullscreen
1 / 31

The diamond concept for the treatment of long bone non- unuions and Bone defects . - PowerPoint PPT Presentation


  • 142 Views
  • Uploaded on

The diamond concept for the treatment of long bone non- unuions and Bone defects . Peter V Giannoudis MD, FRCS Professor & Chairman Academic Department of Orthopaedic & Trauma Surgery University of Leeds, UK . Cortex Periosteum Bone marrow Soft tissue. Classic Knowledge.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'The diamond concept for the treatment of long bone non- unuions and Bone defects .' - lot


Download Now An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide1

The diamond concept for the treatment of long bone non-unuions and Bone defects.

Peter V Giannoudis MD, FRCS

Professor & Chairman

Academic Department of Orthopaedic & Trauma Surgery

University of Leeds, UK

classic knowledge
Cortex

Periosteum

Bone marrow

Soft tissue

Classic Knowledge

Components of Bone Formation

slide3

Fracture Healing………

But what are actually the essential requirements

???????

slide5

Non-hematopoetic, stromal cells

  • Exhibit multilineage differentiation capacity
  • Reside in diverse host tissues
slide6

Fracture HealingEssential Requirements

Osteogenic cells

Osteoconductive matrix

slide8

Fracture Healing Essential Requirements

Osteogenic cells

Osteoconductive matrix

Osteoinductive stimulus

osteoinduction
Osteoinduction

A process which supports the mitogenesis of undifferentiated perivascular mesenchymal cells leading to the formation of osteoprogenitor cells with the capacity to form new bone.

Dr Urist

slide10

Fracture Healing Essential Requirements

Osteogenic cells

Osteoinductive stimulus

Osteoconductive matrix

Favorable mechanical environment

slide12

Mechanical Environment

  • Technique for fracture stabilization
  • Implants for fracture stabilization
  • Surgeon controlled
slide27

Diamond Concept…Issues?

A diamond is precious …

expensive…

MSc’s…………

Scaffold…….

Growth Factor?......

slide28

Efficacy –Results?

Literature?

MSC’s Scaffold Growth Factor

60%-89%

50%-88%

50%-80%

slide29

Diamond Concept…Issues?

A diamond is precious …

expensive…However..!!

  • Patients have undergone 1-2 … even more procedures !!!
  • Soft tissues compromised?
  • Healing potential ?
  • Delayed process of healing?
  • Additional cost implications?
slide30

Diamond Concept…Issues?

A diamond is precious …

expensive… but..

  • Provides Optimum Biological Conditions…
  • Accelerates Fracture healing and consolidation…
  • Facilitates Early Function..
  • Early return to work..

This strategy should be considered in the surgeon’s armamentarium

slide31

MSC’s

Mechanical

Environment

Biology

GF

Scaffold

Conclusion

Conclusion

THANK

YOU!!

DIAMOND CONCEPT!!

Fracture Healing