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Optimal SNR Averaging Strategies for Imaging Noise Reduction

Understand signal-to-noise ratio (SNR), thermal vs. physiological noise, and how to use averaging to mitigate uncorrelated noise in imaging. Learn about noise distributions and strategies for improving SNR in different brain tissues.

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Optimal SNR Averaging Strategies for Imaging Noise Reduction

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  1. SNR • Definition • Averaging uncorrelated noise • Thermal vs. physiological SNR

  2. Averaging to beat down noise If noise is uncorrelated: SNR

  3. Signal-to-Noise Ratio (SNR) • Thermal noise (th) is uncorrelated and normally and uniformly distributed • Imaging noise • Physiological noise (phys) has all sorts of correlations and is different in gray matter, white matter … • Brain noise SNR

  4. Caveat: estimating zero-mean noise in magnitude images Gaussian distribution Rician distribution SNR

  5. Small voxel: low SNR SNR

  6. Big voxel: dominated by phys. noise Phys. noise masked by thermal noise SNR lower in gray matter SNR

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