Clinical Effectiveness of Implantable Cardioverter- Defibrillators Among Medicare Beneficiaries With Heart Failure
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Clinical Effectiveness of Implantable Cardioverter-DefibrillatorsAmong Medicare Beneficiaries With Heart Failure
Adrian F. Hernandez, MD, MHS; Gregg C. Fonarow, MD; Bradley G. Hammill, MS; Sana M. Al-Khatib, MD, MHS; Clyde W. Yancy, MD; Christopher M. O’Connor, MD; Kevin A. Schulman, MD; Eric D. Peterson, MD, MPH; Lesley H. Curtis, PhD
Previous reports have demonstrated that participation in Get With The Guidelines- Heart Failure (GWTG-HF), a national quality initiative of the American Heart Association, is associated with improved guideline adherence for patients hospitalized with HF. We sought to establish whether these benefits from participation in GWTG-HF were sustained over time.
The clinical effectiveness of implantable cardioverter-defibrillators (ICDs) in older patients with HF has not been established, and older patients have been underrepresented in previous studies. The purpose of the paper was to evaluate the clinical effectiveness of ICD therapy in older patients and women to address the potential risks and benefits.
-were aged 65 years or older and were eligible for an ICD,
-had left ventricular ejection fraction of 35% or less, and -were discharged alive from hospitals participating in the Organized Program to Initiate Lifesaving Treatment in Hospitalized Patients With Heart Failure and the Get With the Guidelines–Heart Failure quality-improvement program
Medicare beneficiaries hospitalized with heart failure and LVEF of 35% or less who were eligible for ICD therapy had significantly lower adjusted risk of death over 3 years compared with patients discharged without an ICD. These findings are consistent with the results of randomized clinical trials of ICD therapy.