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This symposium explores how disrupted brain rhythms in Chronic Fatigue Syndrome (CFS) during eyes open and induced mental fatigue conditions may lead to cortical hyper-arousal. The presented "New Model" suggests a link between sleep dysfunction in CFS, EEG hyperactivity, and cortical hyperarousal, proposing a "cumulating sleep-debt model" where reduced sleep efficiency contributes to mental and physical fatigue. Join Chairs Aisha Cortoos and Andreas Ioannides with speakers Lesley Parkinson, Tomas Ros, Alan Parkinson, John Gruzelier, and Rajendra Sharma for insightful discussions on the implications of these findings.
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SAN 2011 • 5th – 8th May Thessaloniki • CHRONIC FATIGUE SYNDROME SYMPOSIUM Chairs: Aisha Cortoos & Andreas Ioannides
Waking Brain Rhythms in CFS Implications For A Model of CNS Dysfunction Lesley Parkinson Tomas Ros, Alan Parkinson, John Gruzelier,Rajendra Sharma.
“New Model” • Disrupted “faster” (>15Hz) brain rhythms in CFS during eyes open and an induced mental fatigue condition(VCPT)is suggestive of cortical hyper-arousal which may explain why cognitive dysfunction worsens with extended workload as the system “burns out”.
“New Model” cont: • There is likely to be a link between sleep dysfunction in CFS and EEG hyperactivity/cortical hyperarousal. • So we have a “cumulating sleep – debt “ model whereby reduced sleep efficiency which is CNS mediated leads to mental fatigue whilst also contributing to physical fatigue.