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Variability of Alcohol and Drug Problems. Continuum from non-use to regular heavy useDiagnostic classifications Substance Abuse and Substance DependenceWider span of problematic use is not captured in diagnostic classifications. Chronic Disease?. NOT all alcohol and drug problems are chronic disordersNo inevitable progression from alcohol abuse to alcohol dependenceSustained use without acceleration is commonDeceleration of alcohol and drug problems with age-related maturation is commo288

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