Pharmacotherapy of Pain: Adjuvant Analgesics. Adjuvant Analgesics. Defined as drugs with other indications that may be analgesic in specific circumstances Numerous drugs in diverse classes Sequential trials are often needed. Adjuvant Analgesics. Multipurpose analgesics
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Alpha-2 adrenergic agonists
Anticonvulsants gabapentin, pregabalin, valproate, lamotrigine
Local anesthetics mexiletine, tocainide
NMDA receptor dextromethorphan, Antagonists ketamine,
Miscellaneous baclofen, calcitonin