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Graves\' disease. Graves\' disease is the most common thyroid abnormality associated with thyroid orbitopathy, but other disorders of the thyroid can have similar ocular manifestations. These include Hashimoto\'s thyroiditis, thyroid carcinoma, primary hyperthyroidism, and neck irradiation.Approximately 40% of patients with Graves\' disease have or will develop thyroid orbitopathy..

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