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DGIS -ITG IMT A. von HUMBOLDT (IMTAvH) Lima, Peru Institutional strengthening & collaboration PowerPoint Presentation
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DGIS -ITG IMT A. von HUMBOLDT (IMTAvH) Lima, Peru Institutional strengthening & collaboration. Lima & UPCH. Lima, massive rural immigration in 1970-1980: 2 10 M Universidad Peruana Cayetano Heredia National General Hospital (4th line)

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slide1

DGIS -ITG

IMT A. von HUMBOLDT

(IMTAvH)

Lima, Peru

Institutional strengthening

& collaboration

slide2

Lima & UPCH

  • Lima, massive rural immigration
  • in 1970-1980: 2 10 M
  • Universidad Peruana Cayetano Heredia
  • National General Hospital (4th line)
  • Northern Lima, 3 million inhabitants
slide3

UNIVERSIDAD PERUANACAYETANO HEREDIAFacultades

Facultad de Medicina “Alberto Hurtado”

Facultad de Ciencias y Filisofía

Facultad de Estomatología

Facultad de Veterinaria y Zootecnia

Facultad de Educación

Facultad de Enfermería

Facultad de Salud Pública y Administración “Carlos Vidal Layseca”

Facultad de Psicología

  • Private University, founded 1962
  • 8 Facs, 6.500 students
  • Hospital: 420 beds, training in 28
  • medical specialities, 900 students
  • 3 Research Institutes,
  • including IMT AvH
slide4

IMTAvH (1968)

  • Clinics for Tropical and Infectious Diseases
  • 150 consultations /day, 36 beds,
  • 9 infectiologists, 3 dermatologists
  • 7 labs
  • 9 courses, pre- & post-graduate incl. Gorgas Course
slide6

IMTAvH- ITG

1987 Spin-off from DGIS/IMTA cooperation with Bolivia

 joint research project EC-STD (INCO) Leishmaniases

1988 Collaboration for Mycobacterioses

Françoise Portaels / Humberto Guerra

1987 Collaboration for Mycoses

Danielle Swinne / Betty Bustamante

1989 Memorandum of Understanding (MoU)

1996 Collaboration in Malnutrition (P. Kolsteren)  joint EC-INCO project Antwerp -Lima - Cochabamba

1996 MoU expanded + Nutrition, Public Health, STD

1998 Framework Programme DGIS-ITG-IMTAvH "International Strenthening & Collaboration"

slide7

COLLABORATION

  • 5 topics 12 partners 4 ITMA departments
  • Leishmaniases *Jorge Arevalo Parasitology
  • cut., muco-cut. Alejandro Llanos-
  • Cuentas, MD
  • *Jean-Claude Dujardin,
  • D Sc
  • Mycobacterioses Humberto Guerra, MD Microbiology
  • TB, MDR-TB, Buruli Françoise Portaels, D Sc
  • Mycoses Betty Bustamante, MD Clinical Sciences & Sporotrichosis Danielle Swinne, D Sc Institute of Public Health Brussels
  • Malnutrition Iris Pecho Public Health Micronutrients, Anna Prada
  • co-infections Patrick Kolsteren
  • Clinical Research Eduardo Gotuzzo Clinical Sciences (since 2000) Tine Verdonck
  • HIV/TB, skin ulcer
  • * Coordination: 2 local coordinators (JA/Lima, JDC/Antwerp) + 1 promotor (DLR/Antwerp)
slide8

SYNERGY BETWEEN TOPICS

      • Clinical epidemiologyofHIV/TB andskin ulcer
      • Molecular tools for diagnosis and epidemiology
  • INSTITUTIONAL STRENGTHENING
      • Human Resources: tech training, M Sc, PhD
      • Centralized equipment for cryobanking & molecular biology
      • Computerized management of reference collections: clinical specimens, pathogens, sera
      • DistanceLearning: CD- ROM Trop. Med. cfr Erwin Van den Ende
slide10

BREAKDOWN 2000

BUDGET 12 M 4

slide11

QUALITY CONTROL

  • 2001  Administrative management: 2nd back-up site visit (LS + JVL)
  •  External evaluation: 1 Lat-Am + 1 EU experts
  • 2002  New 5-yr Master Plan to be identified by IMTAvH
        • institutional priorities
        • QC indicators
        • sustainability
  • DGIS PROGRAMME
  •  Strengthens institutional sustainability
  •  reference and teaching capacity
        •  competitivity in research fund raising: EC-INCO, WHO/TDR, NIH…
slide12

Major achievements (equipment)

  • Improvement of basic laboratory facilities
  • Common facilities for sample storage (-70°C)
  • Bio-Safety
  • Common laboratory facilities for molecular biology
slide13

Major achievements (training)

  • Clinical research: 2 MDs
  • Leishmania: 2 PhD, 4 MSc, 2 MSc
  • Mycology: 1 MSc
  • Mycobacteriology: 5 Medical students, 1 MSc
  • Nutrition: 2 experts, multidisciplinary team
  • Common activities: management biological samples
slide14

Major achievements (science)

Clinical research:

  • TB: many patients with MDR, frequent co-infection PCP-TB
  • Skin ulcer (differential diagnosis): predictive value of clinical and epidemiological information; mostly due to Leishmania, PCR without biopsy (scrap)
  • Translation of CD-Rom on Tropical Medicine in spanish (+/- 75% achieved)
slide15

Major achievements (science)

Leishmania:

  • PCR identification of Leishmania species directly in biopsies (first in the world): prognosis and epidemiological surveillance
  • Development of methodologies for analysis of differential gene expression (virulence, drug resistance)
  • Opening of a research line on the influence of vit A on disease progress
slide16

Major achievements (science)

Mycobacteriology:

  • Implementation of phage-based methodology for identification of Mycobact. infection and determination of drug-resistance
  • Detection of resistance to second line drugs in the general population of TB patients and in patients with MDR-TB (16% kanamycin, 10% ofloxacin)
  • Detection of autochtonous cases of Buruli ulcer
slide17

Major achievements (science)

Mycology:

  • possibility to be regional/national reference centre
  • initiation of studies on molecular epidemiology of fungi

Nutrition:

  • 71% anemia < 5 years: despite good quality of iron-enriched bread, this is not provided to children; search for alternative strategies.
  • Effect of nutritional supplements on parasitoses
slide18

Output (publications)

  • Leishmania: 1 PhD thesis, 1 MSc thesis, 3 papers
  • Mycology: 3 papers
  • Mycobacteriology: 1 manual, 1 paper, 5 abstracts in proceedings
  • Nutrition: reports, papers in the pipeline
  • Clinical research: 1 paper in preparation
slide19

Output (projects)

  • Leishmania: 2 TDR, 1 INCO-Dev (Drug resistance), 1 QOL (epidemiological surveillance)
  • Mycology: 2 clinical trials
  • Mycobacteriology: 1 INCO-Dev (concerted action), 1 submission to TDR
  • Nutrition: 1 INCO-Dev, 1 USAID
  • Clinical research: 2 submissions to TDR
slide20

Ref. Sample

collection

Role of nutritional

status

Molecular diagnosis

and epidemiology

Synergy

Clinical research

Tropical and Infectious diseases

Leishmaniases

Mycoses

Mycobacterioses

HIV/AIDS

slide21

Prospects

  • Clinical trials
  • Reference centre for molecular diagnosis and epidemiology of pathogens (inter-regional course)
  • Immunology (starting from HTLV/Strongyloides)?
  • …(Cysticercose, neuro-)
slide22

DGIS

Institutional strengthening

Stability, continuity, pilot studies for

competitivity in research projects

(EC-INCO, WHO-TDR, NIH..)