DIC is a clinicopathologic syndrome of activated coagulation that manifests with bleeding or thrombosis. Patients with DIC have a loss of balance between the clot-promoting and lysing systems in vivo. This syndrome can have a clinical spectrum ranging from bleeding to a prothrombotic state. DIC is not a specific diagnosis, and its presence always indicates another underlying disease. Bleeding associated with DIC usually results from excess fibrinolysis; thrombosis associated with DIC res140
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