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Recent trends in diet and serum lipids level in Japan. Hirotsugu Ueshima MD Professor and Chairman Department of Health Science Shiga University of Medical Science , Otsu, Japan. Learning objectives. To learn the uniqueness of the trends in mortality from cardiovascular disease in Japan

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recent trends in diet and serum lipids level in japan

Recent trends in diet and serum lipids level in Japan

Hirotsugu Ueshima MD

Professor and Chairman

Department of Health Science

Shiga University of

Medical Science,

Otsu, Japan

learning objectives
Learning objectives

To learn the uniqueness of the trends in mortality from cardiovascular disease in Japan

To learn the trends in fat intake and levels of serum cholesterol in Japan

To learn some unique features of diet style in Japan

slide5

300

AUST

SCOT

USA

NZ

FIN

200

E&W

USSR

SING

100

CHN

JPN

CAN

FRAN

HK

ITY

0

slide6

750

FIN

USA

AUST

SCOT

NZ

CAN

500

SING

USSR

250

ITY

SPN

FRAN

JPN

HK

CHN

0

slide7

240

JPN

USSR

CHN

SCOT

160

AUST

FIN

NZ

USA

ITY

SPN

NOR

SING

FRAN

80

HK

CAN

0

slide8

400

300

R KOREA

USSR

CHN

200

FIN

SCOT

AUST

SPN

NZ

E&W

USA

CAN

100

JPN

0

slide9

Click for larger picture

Click for larger picture

slide10

Click for larger picture

Click for larger picture

slide11

Kodama

Fukuda

5

Konishi

Kitamura

MRFIT

NIPPON DATA80,14-year

4

NIPPON DATA80,Men

NIPPON DAT 80 Women

3

Coronary Heart Dis. (Relative Risk)

2

NIPPON DATA 80

19-year follow-up

Men & Women

1

0

0

1

0

0

150

20

0

30

0

2

50

3

50

Serum total cholesterol (mg/dl)

slide12

Slowing down of declining trend in mortality from ischemic heart disease in Tokyo and Osaka

Click for larger picture

Okayama A, et al. Am J Epidemiol, 2001.

slide13

Trends in Serum Total Cholesterol for Men

Aged 40-59, Cohort Studies in Japan, 1966-1990

Urban Population

Rural Population

Measurement term

Measurement term

Okayama, Ueshima, et al.J Clin Epidemiol,1995

slide14

US 1960-62

US 1976-80

US 1988-91

Total Cholesterol (mg/dl)

JPN 2000

JPN 1990

JPN 1980

Age

slide15

Changes in Energy Percent from Fat,

Protein and Carbohydrate Intake per Capita

National Nutrition Survey in Japan, 1975-97

70

57.4%

60

63.1%

Carbohydrate

50

Percent

40

Fat

26.6%

22.3%

30

20

10

16.0%

Protein

0

1975

1980

1985

1990

1995

1997

slide16
Fat Energy Percent per Capita per Day, Men, by Age Group in 1998, Japan, Excluding alcohol energy, National Nutrition Survey

15-19

20-29

30-39

40-49

50-59

60-69

70-

slide18

Relationship Between Serum Total Cholesterol and 1.35(2S-P)

Serum total cholesterol

Other SCS

Japan, SCS

Japan, 1970s,1985

Intersalt II,Japan

S:Saturated fatty acids

P:Polyunsaturated fatty acids

slide19

20-49Years, 3116Men and Women

National Nutrition Survey, 1994

T-Cho BMI Diet.Fiber Keys Score (mg/dl) (kg/m2) (g)

Men 199.2 23.3 19.8 15.2

Women 192.6 22.0 20.5 14.9

Total 194.9 22.5 20.3 15.0

slide21

Reduction of serum total cholesterol by lifestyle modification

197 hypercholesterolemia, Randomized controlled study

6 Mon. later

8mg/dl diff.

P<0.05

Ueshima H, Okayama A. Education for cholesterol lowering, Hoken Dojin

change in daily salt consumption per capita in japan national nutrition survey 1975 1997
Change in Daily Salt Consumption per Capita in Japan, National Nutrition Survey, 1975-1997
slide23

Trend in Alcohol Consumption per Adult per Year in Japan

National Report on Alcohol Tax Statistics 1963-1995

(L/year)

interlipid
INTERLIPID

Objective

To explore differences in lipid levels and other cardiovascular risk factors between Japanese individuals Living in Japan and in the United States

Presented by Curb D, Ueshima H, et al. in 5th ICPC, Osaka 2001

slide25

Summary (1)

  • Fat intake increased in Japan and the proportion of fat in the diet in young generation became 30 %.
  • Serum total cholesterol level increased during 1980-90 but did not change in the past 10 years. This is explained by slowdown of the increase in fat intake.
  • The difference in serum total cholesterol level between the USA and Japan became 5-10mg/dl in age 30-40 years. In contrast, there was still large difference in that of the elderly people.
slide26

Summary (2)

  • The large difference in coronary heart disease between Japan and the USA is explained in part by the difference in serum total cholesterol level.
  • Other risk factors including HDL-cholesterol, fibrinogen, and alcohol and fish intake may also contribute to the difference in coronary heart disease between the USA and Japan.