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SMAD 2/3 - PowerPoint PPT Presentation


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+. -. cytoplasmic extract. -. +. nuclear extract. p125 FAK. PCNA. I k B a. A. TGF b1. TGF b 1 + a V b 6 block. Ab. TGF b 1 + TGF b -R II block. Ab. TGF b 1. TGF b 1 + a V b 6 block. Ab. TGF b 1 + TGF b -R II block. Ab. control. control. C. N. C. N. C. N. C. N. C.

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Presentation Transcript
slide1

+

-

cytoplasmic extract

-

+

nuclear extract

p125FAK

PCNA

IkBa

A

TGFb1

TGFb1 +

aVb6

block. Ab

TGFb1 +

TGFb-R II

block. Ab

TGFb1

TGFb1 +

aVb6

block. Ab

TGFb1 +

TGFb-R II

block. Ab

control

control

C

N

C

N

C

N

C

N

C

N

C

N

C

N

C

N

SMAD 2/3

SMAD 2/3-P

BxPC-3

Panc-1

K562

B