Christy goff and danielle taylor
Download
1 / 9

Christy Goff and Danielle Taylor - PowerPoint PPT Presentation


  • 118 Views
  • Uploaded on

A randomized, double-blinded, placebo-controlled study of the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management. Christy Goff and Danielle Taylor. Research from article. Lemon Verbena Extract

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Christy Goff and Danielle Taylor' - lavi


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
Christy goff and danielle taylor

A randomized, double-blinded, placebo-controlled study of the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

Christy Goff and Danielle Taylor


Research from article
Research from article the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • Lemon Verbena Extract

    • Used in South America and Southern Europe for asthma, colds, fevers, flatulence, colic, diarrhea, indigestion

    • Verbascoside – main compound with strong AOX and anti-inflammatory properties

    • Plant phytochemicals can have significant protective effects against inflammation-related chronic diseases

  • Fish Oil

    • Shown to have immunomodulatory effects

    • Reduce production of pro-inflammatory eicosanoids in RA


Objective
Objective the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • To test the ability of lemon verbena extract and fish oil supplementation to improve the general condition of joints (pain, stiffness, and function) in subjects already experiencing joint pain.


Methods
Methods the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • Double blind, placebo-controlled, randomized nine week intervention

  • 45 participants enrolled

    • 23 were given the supplement and 22 were given a placebo

    • 14 individuals did not complete the study

  • Weeks 1-5: Consumed 6 capsules per day of 370mg fish oil powder and 230mg of lemon verbena extract for the first five weeks

  • Weeks 6-9: Reduced to 3 capsules daily

  • Completed disease specific questionnaires once a week to measure pain/stiffness, function and physical activity


Results
Results the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • At baseline: No significant different between the treatment group and the placebo group (age, gender, BMI, physical characteristics) using WOMAC and Lequesne’s Functional Index

  • After nine week intervention: A significant improvement of joint stiffness/pain after 3 weeks of supplementation and with function after 4 weeks

    • WOMAC index increased approximately 53% after 9 weeks in the supplementation group and did not decrease in placebo group

    • Decrease in Lequesne’sfunctional index after 4 weeks, dropping 78% compared to baseline


Conclusion
Conclusion the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • First intervention study to show improvement in joint pain management after supplementing with fish oil and herbs after 9 weeks

  • Researches estimate the participants daily intake of lemon verbena extract was between 3000-7000 ORAC units


Limitations
Limitations the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • Strength:

    • Well constructed study – double-blind, placebo controlled, randomized, weekly questionnaires, 2 week washout period

  • Weakness:

    • 14 participants dropped out of the study

    • Did not separately test fish oil vs. lemon verbena

    • Used ORAC value of lemon verbena extract as a criteria for choosing this herb


Comparative information from databases
Comparative information from Databases the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • Natural Medicine Comprehensive Database

    • Lemon Verbena: Used for digestive disorders, agitation, insomnia, asthma, cold, fever, skin conditions, constipation

      • Prepared as a tea, not extract

  • Fish Oil: Used as a treatment for RA

    • Possible effective: Taking fish oil orally, alone or in combination with naproxen, seems to significantly decrease the duration of morning stiffness in patients with RA

    • Use of fish oil might also reduce non-steroidal anti-inflammatory drug (NSAID) requirements when taken together


Comparative information from databases1
Comparative information from Databases the effect of a combination of lemon verbena extract and fish oil omega-3 fatty acid on joint management

  • Up to date:

    • Lemon verbena - No information found

    • Fish oil - found to be associated with low rates of coronary heart disease

  • Natural Standard:

    • Lemon verbena - No information found

    • Fish Oil – Given the letter grade A for rheumatoid arthritis

      • Significant reductions in tender joints and morning stiffness vs dietary controls


ad