Enclomiphene pdf (1)

1. Emclomiphene Citrate is an oral medication that induces ovulation by blocking estrogen receptors. This artificial anti-estrogen effect makes your body believe that estrogen levels are low, which stimulates the production of more follicle stimulating hormone (FSH). Clomiphene citrate acts as a fertility agent in women by inducing superovulation — the release of multiple eggs in a given menstrual cycle. Some form of monitoring is necessary while taking clomiphene citrate. This monitoring may include ultrasounds, blood estrogen levels, and urinary luteinizing hormone (LH) testing. For unexplained infertility, clomiphene citrate is prescribed with intrauterine insemination (IUI). When used for ovulation induction in women who do not ovulate, IUI is not necessary. Ovulation usually occurs between cycle days 14 and 19. Ovulation is the monthly process whereby the female reproductive system produces a mature egg. During ovulation, the brain's pituitary gland releases two hormones: follicle stimulating hormone (FSH) and luteinizing hormone (LH). Together, these hormones are known as gonadotropins. FSH acts as a 'messenger' sent by the pituitary gland to stimulate the development of follicles in the ovaries, each of which will contain one egg. LH is responsible for triggering the release of the egg (ovulation).

2. Common side effects of clomiphene include hot flashes, headaches, abdominal bloating and pain, nausea and vomiting, mood changes, and breast tenderness. Visual symptoms such as blurring, double vision, or seeing spots occur in 1 to 2 percent of women, and usually resolve when treatment stops. Common side effects include vasomotor flushing, pelvic distension and bloating, nausea and vomiting, breast tenderness, visual disturbances and headaches. Ovarian enlargement and uterine bleeding have also been reported. Buy Emclomiphene Citrate Online on: www.onlinegenericmedicine.com Emclomiphene Citrate for ovulation induction Emclomiphene utilized in conjunction with a medication called Provera may be effective in initiating menstruation and ovulation in women who have no menstrual cycle: Treatment begins with a 5-7 day course of Provera, taken orally. Two to three days after Provera is completed, a menstrual period should begin. On the 3rd, 4th or 5th day of menstrual flow, a course of clomiphene is started. An Emclomiphene citrate 50 mg tablet is taken orally for 5 days. On day 11 or 12 of the menstrual cycle, ultrasound monitoring is conducted to determine if an ovarian follicle or follicles have developed. Also at this time, patients are asked to use an ovulation predictor kit to test their urine for a surge in LH (luteinizing hormone) indicating that eggs have matured and ovulation is imminent. If no LH surge is detected, ovulation itself may be triggered with an injection of the medication HCG (Ovidrel), which will cause the release of the mature egg(s) from the follicle(s). Natural intercourse or insemination is timed to ovulation. If ovulation has been assisted by an HCG injection, a form of the hormone progesterone is given via vaginal tablets or gel. The progesterone hormone serves to support the endometrial (uterine) lining and prepare it for the fertilized egg. Two weeks after ovulation, patients are asked to take a home pregnancy (urine) test. If the test is positive, a blood test will be performed to confirm results.

3. If ovulation doesn't occur during this initial clomiphene dosage, another course of provera will be prescribed and the dose of clomiphene increased until ovulation occurs. It may be possible to begin another clomiphene cycle immediately or, if residual cysts are present on the ovarian follicles, a 'rest' cycle may be advised before resuming treatment. If ovulation cannot be induced even with a higher dose of clomiphene, this form of treatment will be discontinued, and ovulation induction may be attempted again using a different form of fertility drug (letrozole or gonadotropins).