Circadian Clock Gene Expression in Peripheral Blood Leukocytes Before Infusion

DESCRIPTION

This study investigates the expression levels of circadian clock genes in peripheral blood leukocytes collected at specific time points before infusion. Blood samples were obtained at predetermined intervals, and gene expression was analyzed through quantitative PCR (qRT-PCR). The results are expressed as fold changes relative to the 09:00 h infusion time, designated as time 0. Key genes studied include Per1, Per2, Bmal1, Cry1, Cry2, Rev-erb, and Rorα, providing insights into circadian rhythm modulation in leukocytes.

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Mar 18, 2014

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Circadian Clock Gene Expression in Peripheral Blood Leukocytes Before Infusion

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Clock Per3 Per1 Cry1 CSNK1 Per2 Fold change Bmal1 Cry2 Rev-erb * * Ror Time Supplemental Figure 1. Circadian clock gene expression in peripheral blood leukocytes prior to infusion. Blood was collected at the indicated time. Gene expression levels were analyzed by qRT-PCR and are expressed as fold change relative to the 09:00 h infusion time, taken to be time 0.

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