1 / 13

U0 7 - 1830

U0 7 - 1830. #840761421 DM with neuropathy, retinopathy with proteinuria. 45 YO African Canadian came in with ESOB. Crea of 1500 mmol/L His baseline Cr was 150 mmol/L in March 2006. PMH: DM x 15 years. Last HgbA1C 14.5% Lab: Anemia, Proteinuria (10 grams/day) Reasons for Biopsy:

lan
Download Presentation

U0 7 - 1830

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. U07-1830 #840761421 • DM with neuropathy, retinopathy with proteinuria

  2. 45 YO African Canadian came in with ESOB. Crea of 1500 mmol/L • His baseline Cr was 150 mmol/L in March 2006. • PMH: DM x 15 years. Last HgbA1C 14.5% • Lab: Anemia, Proteinuria (10 grams/day) • Reasons for Biopsy: • Fast decline of GFR • Patient believes! …………………And Biopsy showed……………….

  3. IF • IgG-Negative. • IgA-Negative. • IgM- Moderate vascular staining. Moderate staining of glomerular hyalinosis lesions. • C3- Mild to moderate vascular staining. Mild to moderate staining of hyalinosis lesions. • C1q- Mild vascular staining. • Kappa-Negative. • Lambda-Negative. • Fibrinogen- Mild staining of fibrous crescent. Mild interstitial staining. • Albumin- Mild linear TBM staining, a common finding in diabetes.

  4. IgM

  5. IgM

  6. C3

  7. C3

  8. Clq

  9. Fibrin

  10. Fibrin

  11. Albumin

  12. EM • Is pending

  13. DiagnosisRenal Biopsy: • Nodular diabetic glomerulosclerosis with extensive parenchymal scarring and atrophy and glomerular scarring nearing end-stage disease.

More Related