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ANFIM PowerPoint Presentation

ANFIM

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ANFIM

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  1. ANFIM Association of Needle Free Injection Manufacturers

  2. ANFIM MISSION The Mission of ANFIM is to promote and protect public health through the advancement of needle-free injection technology. SIGN Conference

  3. ANFIM GOALS • Our Mission is achieved by the accomplishment of the following Goals: • Advocacy: Providing exposure, education, and information to the healthcare, pharmaceutical, and health insurance industries and to consumers. • Image: Creating a positive, professional image for the needle-free industry. • Information: Providing members with access to information regarding industry issues. SIGN Conference

  4. ANFIM MEMBERS • Class 1: Manufacturer • Antares Pharma (Mediject) - Bioject, Inc. • Equidyne Systems, Inc. - Keystone Industries • Class 2: Developer • DCI, Inc. - Felton International • Team Consulting Ltd. - PowderJect Vaccines • Class 3: Related Industry Members • Eli Lilly & Company - Novo Nordisk A/S • Class 4: Representatives from • Centers for Disease Control (CDC) • Program for Appropriate Technology in Health (PATH) • US Food and Drug Administration (FDA) SIGN Conference

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  7. Needle Free Technology • What problems does it solve • Avoids needle stick hazard • No sharps disposal problems • Eliminates the concern for the re-use of needles • Injection pain is reduced in most cases • Speeds the injection cycle • Improved bio-availability of vaccines • Reduces the system cost of injection SIGN Conference

  8. Needle Free History • In use since 1947 • Military • International Public Health Campaigns • Widely used for mass immunizations and disease eradication. • Smallpox (1975) • Polio (when injected) • Measles (Brazil; 1990 to 1996) SIGN Conference

  9. Needle Free Requirements for the Developing World • Safety • Pathogen Transfer Issues • Disposal of Bio-Hazardous Material • Speed • High Thru-put • Ease of Use • Minimize training • Reduce repetitive motion injuries for health care workers • Simplify maintenance and spares logistics • Energy • Should be capable of being self powered • Cost • Must be comparable or less than traditional needle and syringe on a per injection basis SIGN Conference

  10. Review of the Industry • The following slides will provide a company by company review of the state of the art. SIGN Conference

  11. TEAM CONSULTINGwww.team-consulting.com • TEAM is one of the leading product development consultancies in the U.K., primarily serving the medical device and healthcare markets. • Developing CHEMOMOTOR • Motor Technology for Needle-free and Needled Auto-injectors • Low cost energy source • Tailored power profiles • Several thousand injections from a single filled device • Silent operation SIGN Conference

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  14. PowderJectDNA Vaccines Advantages: • Direct Intracellular Delivery • 1,000-fold less DNA than Needle & Syringe delivery • Lower Cost • Safer • Elicits both Antibody and Cellular Responses • Potential for both Px and Rx products SIGN Conference

  15. PowderJectHepatitis B DNA Vaccination • PowderJect has achieved both antibody and cellular responses • PowderJect uses up to 2,500x lower dose PowderJect is the world leader in DNA vaccination SIGN Conference

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  17. Biojectwww.bioject.com • Biojector 2000 • Designed for the professional healthcare market • Immunization programs • Hospitals • Clinics • Self Injectors • Spring powered • CO2 powered with electronics SIGN Conference

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  19. Why Consider the Bioject Needle Free System ? • Proven Technology -- safer, faster, less invasive • Cost savings -- reduces expense of sharps waste disposal • Workforce Protection -- prevents dangerous and expensive needle stick injuries; meets new OSHA safety requirements • Clinical efficacy -- improves vaccine efficacy, faster onset of desired immune response • Operational Flexibility -- safely and quickly gives immunizations, even in non- clinical locations • Patient Compliance -- patients prefer needlefree over the needle and syringe SIGN Conference

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  21. from DCI, Inc. LectraJet HS (high speed) Jet Injection Kit (pat. pend.) For Mass Immunization Campaigns Funding provided byCenters for Disease Control and Prevention (SBIR Contract # 200-2000-10049) Linda D’Antonio, DCI, Inc. LindaD1@twcny.rr.com SIGN Conference

  22. LectraJet HS Key Requirements • Eliminate the risk of cross-infection • High Speed – up to 600 shots per hour SIGN Conference

  23. LectraJet HS • Single-use-auto-disable Ampules • DCI Ampule Management System • Rapid retrieval and ejection of Ampules • No contact with Ampule before or after shot • On-site Ampule filling system • Electrical or Manual Power • Complete injection Kit SIGN Conference

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  28. Issues for Campaigns • Safety • Eliminate risk of pathogen transfer • Re-use of needles • Nozzle contamination • Eliminate sharps disposal • Speed • Up to 600 injections per hour • Cost • Comparable or less than the cost of needle and syringe systems SIGN Conference

  29. Thank You ANFIM

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  32. Oklahoma Preference Survey Graph 2: Clients receiving multiple injection only. Were you satisfied with your needle-free injection method? No = 3% Don't Know Yes = 87% = 10% Results from those clients receiving multiple injections with the Biojector were tabulated, showing an 87% satisfaction rating for the needle-free system. SIGN Conference