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Mitral Valve Surgery Current Practice: Historical Facts. The early history of MV surgery centered on repair The middle history centered on replacementThe current history centers on diagnosis based decisions about repair vs. replacementIs the era of anatomic repair coming to an end?. Mitral Va
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1. Mitral Valve Operations through Standard and Smaller Incisions Published in: The Heart Surgery Forum #2004-1023, 7(4), 2004
4. Describe the population of patients who require mitral valve repair or replacement
Summarize operative results on these patients
Outline the population that may benefit from small incision operations
5. Mitral Valve Replacement (MVR) vs. Mitral Valve Repair (MVV)
6. Operative Categories for All MVR(n=346)
7. Operative Categories for All MVV(n=475)
8. CAB
AVR
Maze
TVV/R
Aortic Root Enlargement
Aortic Root Reconstruction
LVA Resection
Ascending Aortic Reconstruction
Other
9. Operative Incidence for All MVR(n=346)
10. Operative Incidence for All MVV(n=475)
11. Procedure by Diagnosis
12. Prolapse
Ischemic
Rheumatic
Calcific
Annular Dilatation
Prosthetic Valve Dysfunction
Failure of Prior Repair
Endocarditis
Paravalvular Leak
Other
13. Endocarditis
Calcific
Ischemic
Prosthetic Valve Dysfunction
Failure of Prior Repair
Annular Dilatation
Rheumatic
Prolapse
Paravalvular Leak
Other
18. Type of procedure (replacement vs. repair) is a univariate predicator of mortality (p<0.001), but not a predictor in multivariate analysis (p=0.431).
19. Age (decades)
Female
Hx of Renal Failure
Emergent/shock
TV Procedure
NYHA Class IV
20. Comparison of Observed vs. Expected Mortality by Risk Deciles(Multivariate Model)
21. Case Study of Clinical Risk Assessment An 80-year old woman with one previous cardiac operation needs an urgent MVR and AVR.
Age=2
# of Procedures Required = 2
Previous Cardiac Surgery = 1
Operative Urgency =
TOTAL SCORE = 6 (High Risk)
22. All Mitral Cases:% Mortality by # of Procedures
23. All Mitral Cases:% Mortality by Operative Incidence
24. All Mitral Cases:% Mortality by Operative Status
25. All Mitral Cases:% Mortality by NYHA Class
26. Clinical Risk Assessment Model Total Score
1-2
3-5
6+
28. The Future Which technical advances will reduce morbidity and mortality for patients who require mitral valve operation? Is the era of anatomic repair coming to an end?
…3D Echo?
…New Prostheses?
…Robotic Approaches?
29. Identifying Patients Eligible for Less Invasive Incisions: 1/97-12/02
30. Identifying Valve Patients Eligible for Less Invasive Incisions: 1/97-12/02
31. Conversion to Full Sternotomy Events that may require conversion to full sternotomy:
Inadequate exposure
Bleeding
Hypotension
32. Increasing Use of Limited Incision in Eligible Mitral Cases: 1/97-12/02
33. Patient CharacteristicsMitral Valve Repair (n=261)
34. Patient CharacteristicsMitral Valve Replacement (n=95)
35. Postoperative OutcomesMitral Valve Repair (n=261)
36. Postoperative OutcomesMitral Valve Replacement (n=95)
37. Limited Incision Intracardiac Surgery Conceptual guidelines for smaller incision valve operations (anatomic repair):
Should not be much more difficult
Should not take much longer
Should not be more expensive
Should not utilize groin cannulation
Should not be uglier
38. Techniques: Incision Limited median sternotomy (8-10 cm)
Right Inframammary thoracotomy
(10-15 cm)
39. Techniques: CPB Ascending aortic cannulation
Venous: vacuum assisted
Single right atrial – limited sternotomy
Bicaval – inframammary thoracotomy
Myocardial protection:
Antegrade
Retrograde cardioplegia using TEE
41. Expected Benefits: Lower Mortality
Lower Morbidity – particularly stroke
Shorter Length of Stay
Less Cost
Quicker Rehabilitation
Higher Patient Acceptance and/or Cosmesis
42. New technology often follows the law of unintended consequences…
43. Consequences: Aortic side biting in a working heart
Groin cannulation and/or intra-arterial manipulation
Longer operating times and clamp times
44. New technology is being sold to practitioners before there are convincing data that the new technology is as good as the current technology
45. The repair and replacement populations have substantially different preoperative characteristics, diagnoses, and outcomes
The results of repair are much better than those of replacement because the populations are so different
About 40% of mitral valve patients are eligible for smaller incision operations
At present, we perform MVR and MVV via smaller incisions in about 25-30% of all MV patients