高分子的设计与合成

1. 高分子的设计与合成 洪春雁 潘才元

2. 聚合物的结构Architectures of polymers 线形聚合物 Linear polymers 均聚物 PE, PP, PS, PVC etc. 嵌段共聚物 无规共聚物 交替共聚物

4. 非线形聚合物Nonlinearpolymers Comb Polymer Grafting Polymer 接枝聚合物 梳形聚合物

5. H- shaped and -shaped copolymers

6. 星形聚合物 Star polymers 星形杂臂聚合物 Miktoarm star polymers

7. Mono-Dispersed • Nano-Sized • Egg-Like • High density of surface Functional groups

8. Hyperbranched polymers Umbrella Copolymer 伞形聚合物 Dumbbell-shaped copolymers 超支化聚合物 哑铃形聚合物

9. 环状聚合物

10. 原子转移自由基聚合 Atom Transfer Radical Polymerization, ATRP ATRP or Atom Transfer Radical Polymerization is a Polymerization reaction involving free radicals. It was introduced as an extension to ATRA or Atom Transfer Radical Addition by Jinshan Wang and Matyjaszewski, (1995) and Sawamoto (1994/5).

11. DrKrzysztof Matyjaszewski J.C. Warner Professor of Carnegie Mellon UniversityDepartment of Chemistry4400 Fifth AvenuePittsburgh, PA 15213 Dr. Mistuo Sawamoto Department of Polymer Chemistry Graduate School of Engineering Kyoto University, Kyoto

18. Mask Streptavidin Scale bar = 25 µm

19. RAFT Polymerization RAFT=Reversible Addition-Fragmentation Chain Transfer Polymerization

20. Dr. Graeme Moad CSIRO Molecular and Health Technologies, Bayview Avenue, Clayton, Victoria 3168, Australia He joined CSIRO as a research scientist in 1979 and is currently a chief research scientist. Dr Moad is coauthor of the book ‘The Chemistry of Free Radical Polymerization’ which appeared as a second edition in 2006. His research interests lie in the fields of polymer design and synthesis (free radical polymerization, reactive extrusion), polymerization kinetics and mechanism, and most recently polymer nanocomposites.

21. Dr. Ezio Rizzardo CSIRO Molecular and Health Technologies, Bayview Avenue, Clayton, Victoria 3168, Australia Ezio Rizzardo is a graduate of the University of New South Wales and received his Ph.D. from the University of Sydney for his studies on the photochemistry of nitro compounds. He joined CSIRO in 1976 after a postdoc at Rice University, RIMAC, and the Australian National University. His CSIRO research has focused on developing methods for controlling free radical polymerization. For this he has received a number of awards including the RACI Australian Polymer Medal and the CSIRO Chairman’s Gold Medal. Currently he is a CSIRO Fellow and a Fellow of the Australian Academy of Science.

22. Dr.San H. Thang CSIRO Molecular and Health Technologies, Bayview Avenue, Clayton, Victoria 3168, Australia San H. Thang was born in Saigon, Vietnam, in 1954 and came to Australia in 1979 as a refugee. He completed his B.Sc.(Hons) degree in 1983 and Ph.D. in 1987 from Griffith University. He joined CSIRO in 1986 as a research fellow. He then moved to ICI Australia in late 1987 to undertake the challenge of industrial research. He returned to CSIRO in late 1990, and in 1995 he was co-inventor of the RAFT Process. He is currently a senior principal research scientist at CSIRO Molecular and Health Technologies where his research focuses on the interface between organic and polymer chemistry.

27. Click Chemistry

30. 蝌蚪形聚合物的合成

32. Thiol-Click

33. Michael addition reaction • Arthur Michael (1855–1942), who discovered the Michael addition reaction. (b) Schematic depiction of the Michael addition reaction.

34. General carbon-Michael reaction mechanistic scheme.

35. Second Michael addition of acetoacetate group to methyl acrylate. Michael Addition involving an alkyne acceptor.

36. Higher reactivity of secondary amines in aza-Michael addition reactions.

38. Dendrimer

40. Alanine Ala A nonpolar neutral 1.8 Arginine Arg R polar positive -4.5 Asparagine Asn N polar neutral -3.5 Aspartic acid Asp D polar negative -3.5 Cysteine Cys C nonpolar neutral 2.5 Glutamic acid Glu E polar negative -3.5 Glutamine Gln Q polar neutral -3.5 Glycine Gly G nonpolar neutral -0.4 Histidine His H polar positive -3.2 Isoleucine Ile I nonpolar neutral 4.5 Leucine Leu L nonpolar neutral 3.8 Lysine Lys K polar positive -3.9 Methionine Met M nonpolar neutral 1.9 Phenylalanine Phe F nonpolar neutral 2.8 Proline Pro P nonpolar neutral -1.6 Serine Ser S polar neutral -0.8 Threonine Thr T polar neutral -0.7 Tryptophan Trp W nonpolar neutral -0.9 Tyrosine Tyr Y polar neutral -1.3 Valine Val V nonpolar neutral 4.2 Amino Acid   Hydropathy index Side chain polarity

41. Synthesis of L-valine and L-leucine type Ib dendrimers: (a) Boc-Gly-OH, DCC, DMAP-DCM; (b) TFA-DCM; (c) active ester, HOBt, DIEA, DMF-DCM; (d) Ac2O, DIEA-DC

42. Photon Is Dendrimer an Antenna?

43. Cis- and trans- transformation ofazobenzene Irradiation at 1600 cm-1 can make the transformation of cis- to trans-?

44. Photoisomerization of Azodendrimer by Harvesting ofLow Energy Photons Photons (1600 cm-1)

46. G2 dendrimers containing Coumarin-2 as an energy donor and Coumarin-343 as an energy acceptor (left) and dendrimers without Coumarin-343 chromophore (right) for relative rate study.

48. Organic Light Emitting Diodes

49. Catalysis http://perceco2.chem.upenn.edu/~percec/inthenews/denx.html http://www3.interscience.wiley.com/cgi-bin/fulltext/106558159/PDFSTART

50. Nanowires