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Multimistura is an alternative dietary supplement - high nutritional value - low cost

Multimistura is an alternative dietary supplement - high nutritional value - low cost - destined mainly to undernourished children - formulated with several ingredients - use of alternative ingredients - preference for locally available products. Multimistura

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Multimistura is an alternative dietary supplement - high nutritional value - low cost

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  1. Multimistura is an alternative dietary supplement - high nutritional value - low cost - destined mainly to undernourished children - formulated with several ingredients - use of alternative ingredients - preference for locally available products

  2. Multimistura • May be formulated using different raw materials • Flexibility to produce according to • Regional availability • Nutritional requirements of a given population

  3. Multimistura • Recent studies carried out at LRi/CENA/USP • Composition assessment of different • Formulations • Constituents • Findings • Large variations among nutrient concentrations • Possibility to produce different formulations • Fulfill specific nutritional requirements

  4. Multimistura nutritional value

  5. Multimistura’s nutritional value is comparable to commercial supplements

  6. Multimistura compared to commercial supplements nutritional composition

  7. Multimistura compared to commercial supplements dietary minerals

  8. Chemical elements in food usually present a large range of variation Multimistura and its ingredients should be carefully evaluated Selenium taken as example

  9. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  10. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  11. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  12. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  13. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  14. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  15. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  16. Multimistura and its ingredients First results of chemical elements evaluated by instrumental neutron activation analysis (INAA)

  17. Multimistura • High potential for supplying mineral nutrients • Extremely positive cost/benefit • Example • Recommended dose of a multimistura for 1-3 year old children = only 10 g/day • Very low cost

  18. Multimistura • Example – mineral nutrients • This small daily portion can supply the DRI requirements for • All chromium and manganese • 50% of magnesium • Near one third of copper, iron and zinc

  19. STUDY OF CHEMICAL ELEMENTS IN MULTIMISTURA AND ITS INGREDIENTS Why using neutron activation analysis?

  20. Neutron activation analysis: - is a multi-element capable technique - does not need sample dissolution - can be performed at a high metrological level RELIABLE RESULTS!

  21. Neutron activation analysis was recently approved by CCQM/BIPM as a primary method The President said that although the CCQM had not discussed the list of ‘potentially primary methods’ during recent years, it was recognised that NAA had claims to a similar status to that of the five methods listed originally by the CCQM and that NAA will be added to that list.

  22. CCQM Primary Methods • Isotope Dilution Mass Spectrometry • Coulometry • Gravimetry • Titrimetry • Determination of Freezing Point Depression • Neutron Activation Analysis

  23. Example of INAA performance compared to IDMS CCQM-K49/P85 – Bovine Liver +1 STD RV CENA -1 STD Adapted from: R. R. Greenberget al 2007Preliminary Results

  24. Example of INAA performance compared to IDMS CCQM-P29/K24 – Rice +U KCRV -U Adapted from: Y. Aregbe et al 2003 Metrologia 40

  25. STUDY OF CHEMICAL ELEMENTS IN MULTIMISTURA AND ITS INGREDIENTS Why is CENA/USP qualified for such study?

  26. Quality System • Radioisotopes Laboratory – CENA/USP • operates according to • NBR ISO/ IEC 17025 • implementation started in1996 • international recognition by IAEA in 2002 (IAEA: International Atomic Energy Agency)

  27. CENA/USP hosts The Brazilian Satellite Centre of Trace Element Institute for UNESCO

  28. Demonstration of analytical competence: Metrology in Chemistry – participation in CCQM Bureau International des Poids et Mésures (BIPM) Sèvres, Paris, France Consultative Committee for Amount of Substance (CCQM)

  29. Metrology in Chemistry Participation in CCQM – Inorganic Analysis Working Group - 14 participations - 12 elements - 12 materials

  30. Metrology in Chemistry SEVERAL PARTICIPATIONS IN THE CCQM INVOLVING FOOD SAMPLES SOME EXAMPLES

  31. CCQM-P39.1 and CCQM-K43 – Salmon +U KCRV -U Adapted from: Y. Aregbe et al 2006 Metrologia 43

  32. CCQM-P29/K24 – Rice +U KCRV -U Adapted from: Y. Aregbe et al 2003 Metrologia 40

  33. CCQM-K49/P85 – Bovine Liver +1 STD RV CENA -1 STD Adapted from: R. R. Greenberget al 2007Preliminary Results

  34. CCQM-P39 – Tuna Fish CI 95% Reference Value Adapted from: Y. Aregbe et al 2004 Metrologia 41

  35. CCQM-P64 –Nonfat Soybean Powder +2 STD RV CENA -2 STD Adapted from: Ma Liandiet al 2006 Report – Draft A

  36. Welcome to the Radioisotopes Laboratory… Waterpaint by Prof. Klaus Reichardt (Nikolaus), 1996 Stained-glass door of the gamma spectrometry room

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