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This study investigates the impact of varying concentrations of Dex (Dexamethasone) and EtOH (Ethanol) on osteoclast number and activity in relation to TNFα and 1,25-dihydroxyvitamin D3. Specimens treated with 0 nM and 100 nM Dex, alongside control groups, are compared to analyze changes in osteoclast formation and function. Understanding these interactions is crucial for developing therapeutic strategies for bone-related disorders.
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Osteoclast number 0nM Dex 100nM Dex 0nM Dex 100nM Dex control EtOH TNFα/1,25(OH)2D3