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Bob Cumming (SPH) Lead Investigator

Bob Cumming (SPH) Lead Investigator Fiona Blyth, Helen Creasey , David Handelsman, Hal Kendig , David Le Couteur, Vasi Naganathan, Markus Seibel, Philip Sambrook, Steve Simpson, Louise Waite . WHY DO WE GET OLD???. CHAMP Study Population. Males aged 70 years and over

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Bob Cumming (SPH) Lead Investigator

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  1. Bob Cumming (SPH) Lead Investigator Fiona Blyth, Helen Creasey , David Handelsman, Hal Kendig, David Le Couteur, Vasi Naganathan, Markus Seibel, Philip Sambrook, Steve Simpson, Louise Waite

  2. WHY DO WE GET OLD???

  3. CHAMP Study Population • Males aged 70 years and over • Resident in Burwood, Canada Bay or Strathfield LGAs • Live in community (not nursing home) • Sampled from electoral roll • Baseline measures repeated • Two years • Five years (? Seven years) • 4 monthly phone calls to ascertain falls, fractures, hospital admissions, nursing home/hostel admission • Informant interviews by phone

  4. Measurements: broad and rich Self-completed questionnaire (1 hour) THEN Clinic visit (3 hours) • Blood tests (80 mls) • Cognitive function • Questionnaire • Muscle strength • Urinary function • DEXA (bone, muscle, fat)

  5. Progress to Date • Recruitment and baseline data collection: Jan. 2005 to May 2007 • 1705 subjects recruited • 2 year follow-up: Feb. 2007 to October 2009 • 1367 subjects seen at clinic (80%) • 5 year follow-up: - Commenced August 2010 (currently 87% participation rate) Expected total 1100 • Total of 235 deaths to date (and rising)

  6. Outputs 4 completed PhDs 5 current PhDs Nested case-control study (sirtuins and longevity) Prevalence and treatment of osteoporosis in older Australian men Depressive symptoms in older male Italian immigrants in Australia Pain, frailty and comorbidity in older men Determinants of serum-induced SIRT1 expression in older men Drug Burden Index and physical function in older Australian men Subjective social support in older male Italian–born immigrants in Australia Estimation of lean body weight in older men

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