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Mrs Stewart Honors Biology. Pedigree Charts. What is a pedigree?. Pedigree Charts. Record ancestry and/or trace the geneology of a trait through the family lines. Genetic Testing Medical History Historical Data Family Records. Why do we use them?

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pedigree charts1
Pedigree Charts

Record ancestry and/or trace the geneology of a trait through the family lines

  • Genetic Testing
  • Medical History
  • Historical Data
  • Family Records

Why do we use them?

Then what information do we use to determine inheritance of traits?

how is hemophilia inherited
How is Hemophilia inherited?

Sex-Linked Recessive Disorder

example hemophilia in the royal family1
Example: Hemophilia in the royal family

What are some clues that you can see in this pedigree that could tell you this is a sex-linked disorder?

  • Albinism
  • Polydactyly
how do we read a pedigree
How do we read a Pedigree?
  • Bill
  • Sam

Pam is Ann’s Grandmother

Which family members are Albino?

How is Ann related to Pam?

what are inheritance patterns
What are Inheritance Patterns?

Inheritance Pattern: The transmission of genetically encoded traits/conditions/diseases to offspring

In other words: How the gene is transmitted/passed on.

autosomal recessive
Autosomal Recessive

Skips generations

Affects males/females equally

Pedigree may show carriers

autosomal dominant
Autosomal Dominant

There will not be carriers – those with the gene will be “affected”

Will probably not skip generations

Will affect males/females equally

sex linked recessive
Sex-Linked Recessive

More males affected than females

Skips generations

autosomal recessive1
Autosomal Recessive
  • How do we know?
    • “affected” skips generations
    • carriers
enrichment assignment
Enrichment Assignment
  • Create a family pedigree for the following trait:
    • Ability to taste “bitter”
  • Mrs. Stewart has strips of paper called PTC paper that will determine this ability.

The ability to taste PTC (bitter) is inherited.

BB = strong bitter taster

Bb = somewhat able to taste bitter

bb = cannot taste bitter

how to complete the enrichment assignment
How to complete the enrichment assignment:

15 possible enrichment points

Have each family member (immediate household family) taste the PTC paper.

Use their responses to identify their genotypes

Create a pedigree that shows the trait throughout your family

10 points extra if you include pictures of each family member while tasting the PTC paper.