Use of MDCK Cells for Manufacture of Inactivated Influenza Vaccines: Introduction. Philip R. Krause, M.D. Outline. Definitions and brief introduction to the issues Recent history of thinking about neoplastic cell substrates
Philip R. Krause, M.D.
Manufacturers will provide more detail
1958, MDCK established from healthy female cocker spaniel
From Gaush, PSEBM, 1996 122:931
The next slides will describe the past 10 or so years of CBER thinking about introduction of neoplastic cell substrates
The next slides will summarize the concerns that may be associated with introducing new neoplastic cell substrates