slide1 n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Bavarian Reperfusion Alternatives Evaluation 2: PCI versus medical therapy in late-presentation MI patients PowerPoint Presentation
Download Presentation
Bavarian Reperfusion Alternatives Evaluation 2: PCI versus medical therapy in late-presentation MI patients

Loading in 2 Seconds...

play fullscreen
1 / 5

Bavarian Reperfusion Alternatives Evaluation 2: PCI versus medical therapy in late-presentation MI patients - PowerPoint PPT Presentation


  • 124 Views
  • Uploaded on

BRAVE-2 Trial. Bavarian Reperfusion Alternatives Evaluation 2: PCI versus medical therapy in late-presentation MI patients. Presented at The American College of Cardiology Scientific Sessions 2005 Presented by Dr. Adnan Kastrati. BRAVE-2 Trial.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Bavarian Reperfusion Alternatives Evaluation 2: PCI versus medical therapy in late-presentation MI patients' - keran


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide1

BRAVE-2 Trial

Bavarian Reperfusion Alternatives Evaluation 2: PCI versus medical therapy in late-presentation MI patients

Presented at

The American College of Cardiology

Scientific Sessions 2005

Presented by Dr. Adnan Kastrati

brave 2 trial
BRAVE-2 Trial

365 patients with MI presenting >12 hours after symptom onset

Without ongoing chest pain or Killip class 3/4

Invasive

Angiography, then PCI if necessary

Mean randomization to PCI time: 1.5 hrs

Conservative

Conventional medical therapy

  • Endpoints:
    • Primary – Infarct size determined by SPECT at 5-10 days
    • Secondary – Death, MI, stroke, at 30 days

ACC 2005

brave 2 primary endpoint
BRAVE-2: Primary endpoint

Infarct Size

(% of left ventricle)

p = 0.002

  • The primary endpoint of infarct size determined by SPECT at 5-10 days was significantly lower in the invasive arm compared to the conservative arm.

ACC 2005

brave 2 secondary endpoints
BRAVE-2: Secondary Endpoints

At 30 days, there was no statistically significant difference in clinical end points between the invasive and conservative arms.

p = 0.37

p = 0.4

p = 0.21

ACC 2005

brave 2 summary
BRAVE - 2: Summary
  • Among patients with MI presenting more than 12 hours after symptom onset, invasive treatment was associated with a significant reduction in the primary endpoint of infarct size compared to conservative treatment with medical therapy
  • Clinical endpoints of death, MI and stroke were similar between the groups at 30 days
  • Further evaluation of the benefit of PCI among late-presenting asymptomatic STEMI patients appears warranted

ACC 2005