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This study explores the differences in secretome profiles of breast cancer cell lines MCF7 and T47D, focusing on their interactions with different microenvironments. The analysis reveals unique regulatory mechanisms that influence cellular secretion patterns, shedding light on potential therapeutic targets.
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A * * * * B MCF7/CAF18-CM MCF7/NAF-CM MCF7/CAF8-CM MCF7 * T47D T47D/CAF18-CM T47D/CAF8-CM T47D/NAF-CM CAF18 GFP-CM CAF18 shIL-6-CM MCF7 SupplementaryFigure 4