VENTILATION/PERFUSION & GAS EXCHANGE. AIMS. What factors are important in gas exchange?. What factors affect gas transfer?. What is the ventilation/perfusion ratio?. GAS EXCHANGE. ADEQUATE ALVEOLAR VENTILATION (V A ) TRANSFER OF GAS ACROSS ALVEOLAR-CAPILLARY MEMBRANE
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Where, P= pressure gradient
A= surface area
Mw= molecular weight
Gas transfer is directly proportional to pressure difference, surface area, & inversely to thickness- Fick’s law.
Efficiency of gas exchange is increased if ventilation and perfusion are matched.
CO2, T, 2,3 DPG, pH