Aloe Vera: Nature’s Versatile Herb!. Presented by Walt C Jones Chairman International Aloe Science Council. INTERNATIONAL ALOE SCIENCE COUNCIL.
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Walt C Jones
International Aloe Science Council
Dedicated to Increase Awareness and the Quality of Aloe Vera Through Education, Research, Certification of Raw Materials, and Certification of Finished Goods
Founded in 1981
Aloe vera has the highest positive consumer recognition – “with Aloe”
Aloe vera raw material market estimate at $125 million
Products being sold “with aloe” is estimated at $110 billion
Over 10,000 new products are introduced each year that contains aloe vera as an ingredient
Ask a room full of Herbalist the ONE herb they would want on deserted island….ALOE!
Review and revision of existing monographs for “the drug aloe” are needed
Specifications and analytical methods for qualitative and quantitative markers as well as potentially bioactive constituents such as aloe polysaccharides need to be established
Monograph(s) for the medicinal herb aloe are required to differentiate medicinal (or dietary supplement) aloe from “the drug aloe”
Aloe used in studies must be characterized by established specifications
The IASC is spearheading these initiatives in collaboration with ABC, AHPA, USP and other herbal organizations world wide
When the Aloe industry begins to routinely use government-recognized validated assays to ensure the efficacy of commercial products, consumers will consistently experience the astonishing benefits of fresh Aloe.
Egyptian – Papyrus ebers about 1550BC
Greek – Hippocrates 460BC – 375BC)
Greek – Celsus (25BC – 50 AD)
Greek – Dioscorides (41AD – 68AD)
First Mechanism of Action of Acemannan
Second Mechanism of Action of Acemannan
Intake of vitamins and supplements is associated with better health & longevity
60% of the US population consumes vitamins and other supplements
The elderly population that consumes these vitamins/supplements is on the increase, and they are prone to deficiencies of some vitamins such as vitamin B12.
Aloe Vera is a common house plant that has been used for its health benefits for centuries in many different cultures.
S. Devaraj, PhD, DABCC, FACB
Director of Toxicology
Laboratory for Atherosclerosis and Metabolic Research, UCDavis Medical Center
External uses: Aloe gel has historically been used for soothing, minor burns and skin irritations.
Internal uses: used as a digestive aid and immune system booster.
A recent consensus points to 60% of elderly population consuming Aloe containing products
Aloe Vera may enhance the bioavailability of vitamin E and vitamin C.
Biologically significant ingredients in Aloe are primarily thought to be the polysaccharides such as Acemannan, but could include some of the other 200+ components
1.) Number of people taking vitamins and supplements is 60% and growing.
2.) Numerous environmental & other factors impair the bioavailability of the common water-soluble vitamin C-a potent antioxidant that also aids in iron absorption and collagen synthesis.
3)Vitamin B12 is another common water soluble vitamin that is not well-absorbed in older individuals and is low in vegetarians
Most people do not consume 5 daily servings of fruits or vegetables, thus supplements such as Aloe that may increase the absorption of vitamins can be helpful, especially in the older population.
Primary: To test the effect of two different Aloe Vera preparations on the bioavailability of Vitamin C and B12 in healthy human volunteers.
Secondary: To test the effect of two different Aloe Vera preparations on the lipid profile and glucose levels since Aloe supplements contain different polysaccharides.
Fasting blood draw
Patient either receives Aloe vera gel, (whole) leaf extract or a placebo in a random order( on each of the 3 visits).
And 500mg of Vitamin C along with 1mg of Vitamin B12.
7 samples of blood were taken from the patient at each visit.
At 0, 1,2, 4, 6, 8, 24 hours.
At 2 hours, subjects were given a light breakfast (bagel and banana) and at 6 hours, they were provided a light lunch (fettucine or special pizza with no vitamin C or B12).
Aloe Vera Gel and Leaf preparations were well-tolerated by subjects and they experienced no side effects
Aloe vera Gel and Leaf had no effect on the lipid profile or on glucose levels
When given with vitamins C and B12, Aloe vera Gel significantly increased plasma ORAC at both 4 and 24 hrs and Aloe vera Leaf significantly increased plasma ORAC at 4 hrs compared to baseline and placebo
When given with vitamins C and B12, Aloe vera Gel significantly increased plasma vitamin C at 4,6,8 and 24 hrs and Aloe vera Leaf significantly increased plasma vitamin C at 4 and 6 hrs compared to baseline and placebo
When given with vitamins C and B12, Aloe vera Gel and Leaf significantly increased serum vitamin B12 levels at 1 and 2 hrs compared to baseline and placebo
Aloe Gel and Aloe Leaf preparations are safe, well-tolerated and enhance the bioavailability & antioxidant potential of vitamins C and B12.
This could have major implications with regards to supplementation with vitamins/supplements, especially in older populations.
Aloe Vera, taken with vitamins & supplements, help enhance the body’s ability to assimilate them
Aloe Vera is now gaining the needed science that supports the anecdotal recognition of aloe’s myriad health benefits
IASC organization is spearheading the regulatory, legislative, scientific, and marketplace acceptance of the many benefits of aloe vera