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This article explores the intricate processes of apoptosis receptor editing within the context of B-lymphocyte signaling. It focuses on the Blys (B-lymphocyte stimulator) and BCR (B-cell receptor) pathways relevant in T1 and T2 B-cell subtypes. By analyzing the effects of various conditions such as Pro-B and Pre-B stages, and considering the role of different immunological checkpoints (IMC), we delve into how receptor dynamics impact cell survival and programmed cell death. This research contributes to a better understanding of immune responses and potential therapeutic avenues.
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MZB Blys Blys BCR T1 T2 Pro-B FB Pre-B IMC c-Rel p65 p50 p52 p50 p65 p50 p65 c-Rel p50 (p65) (p52) (RelB) Apoptosis Receptor editing