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Investigating Tyrosine-Phosphorylation of β-Catenin Y-F Mutants

The study explores the tyrosine-phosphorylation of β-catenin Y-F mutants. Results show reduced phosphorylation in these mutants but not complete elimination. The findings shed light on the role of tyrosine residues in β-catenin signaling pathways.

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Investigating Tyrosine-Phosphorylation of β-Catenin Y-F Mutants

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  1. Y86F+Y654F Y333F WT Y86F Y654F IB: p-Tyr (β-catenin) 1.0 0.4 0.5 0.4 0.4 IB: LaminB Supplementary Figure S4 Tyrosine-phosphorylation of β-catenin Y-F mutants. Note that β-catenin Y-F mutants were less phosphorylated, but not eliminated.

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