slide1
Download
Skip this Video
Download Presentation
Sotheavy Vann Ngoc Phan

Loading in 2 Seconds...

play fullscreen
1 / 11

Sotheavy Vann Ngoc Phan - PowerPoint PPT Presentation


  • 119 Views
  • Uploaded on

Evidence that talin alternative splice variants from Ciona intestinalis have different roles in cell adhesion. Sotheavy Vann Ngoc Phan. What are Talins?. Modular cytoskeletal proteins-cell adhesions Talin 1 and 2 have non-redundant roles Talin 1-focal cell adhesion and cellular motility

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Sotheavy Vann Ngoc Phan' - karim


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide1

Evidence that talin alternative splice variants from Ciona intestinalis have different roles in cell adhesion

Sotheavy Vann

Ngoc Phan

what are talins
What are Talins?
  • Modular cytoskeletal proteins-cell adhesions
  • Talin 1 and 2 have non-redundant roles
    • Talin 1-focal cell adhesion and cellular motility
    • Talin 2-lables F-actin stress fibers for stable adhesion assemblies
    • C. Intestinalis-talin a and talin b
  • Why study talins?
ciona intestinalis
Ciona Intestinalis

http://www.google.com/url?source=imglanding&ct=img&q=http://cfb.unh.edu/phycokey/Choices/Anomalous_Items/Chordates/tunicates/tunicate_03_600x450_larvae_riley_nolan.jpg&sa=X&ei=XLiFT9ePDYie8gT15cXCCA&ved=0CA0Q8wc4FQ&usg=AFQjCNGQ0Y-9A4X0sBmrUGdJaCGDTbektg

Phylum Chordata

Life Cycle

Good Model Organism

http://upload.wikimedia.org/wikipedia/commons/thumb/f/fe/Cionaintestinalis.jpg/220px-Cionaintestinalis.jpg

expressed sequence tag
Expressed Sequence Tag
  • Gene Discovery Tool
  • EST Method
    • Involves the Central Dogma of genetics
  • Other Methods
    • Searching for signal sequences
    • Comparing genomes
ad