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ISHLT. ISHLT. J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132. HEART-LUNG TRANSPLANTATION. Overall. 2011. ISHLT. ISHLT. J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132. NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR.

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heart lung transplantation

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

HEART-LUNG TRANSPLANTATION

Overall

2011

number of heart lung transplants reported by year

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

NUMBER OF HEART-LUNG TRANSPLANTS REPORTED BY YEAR

NOTE: This figure includes only the heart-lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of heart-lung transplants worldwide has declined in recent years.

2011

average center volume heart lung transplants january 1 1998 june 30 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

AVERAGE CENTER VOLUMEHeart-LungTransplants: January 1, 1998 - June 30, 2010

2011

slide4

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY CENTER VOLUMEHeart-Lung Transplants: January 1, 1998 - June 30, 2010

2011

slide5

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

DISTRIBUTION OF HEART-LUNG TRANSPLANTS BY LUNG CENTER VOLUMELung Transplants: January 1, 1998 - June 30, 2010

2011

heart lung transplantation kaplan meier survival for all ages transplants january 1982 june 2009

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for All Ages(Transplants: January 1982 - June 2009)

2011

heart lung transplantation1

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

HEART-LUNG TRANSPLANTATION

Adult Recipients

2011

diagnosis in adult heart lung transplants january 1982 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS (January 1982 - June 2010)

“Other” includes cancer, LAM, OB, sarcoidosis, bronchiectasis

2011

diagnosis in adult heart lung transplants transplants january 1982 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS(Transplants: January 1982 - June 2010)

2011

diagnosis in adult heart lung transplants by era transplants january 1982 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

DIAGNOSIS IN ADULT HEART-LUNG TRANSPLANTS BY ERA(Transplants: January 1982 - June 2010)

“Other” includes OB (non-ReTX) and Bronchiectasis

2011

adult heart lung transplantation major indications by year

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTATIONMajor Indications By Year (%)

2011

adult heart lung transplantation major indications by year number

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTATIONMajor Indications By Year (Number)

2011

slide13

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2010

2011

slide14

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATION Transplants between January 2000 and June 2010

2011

slide15

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTS:DONOR AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2010

2011

slide16

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients(Transplants: January 1982 - June 2009)

2011

slide17

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival for Adult Recipients by Era(Transplants: January 1982 - June 2009)

2011

slide18

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2009)

2011

slide19

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis Conditional on Survival to 1 Year(Transplants: January 1990 – June 2009)

2011

slide20
ADULT HEART-LUNG RECIPIENTS Cross-Sectional Analysis Functional Status of Surviving Recipients (Follow-ups: April 1994 – June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

2011

slide21
ADULT HEART-LUNG RECIPIENTSFunctional Status of Surviving Recipients US Recipients Only(Follow-ups: March 2005 - June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

2011

slide22

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTSEmployment Status of Surviving Recipients(Follow-ups: April 1994 – June 2010)

2011

slide23

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTS:Rehospitalization Post-transplant of Surviving Recipients(Follow-ups: April 1994 - June 2010)

2011

slide24

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTS Induction ImmunosuppressionFor transplants between January 2001 through June 2010

2011

Analysis is limited to patients who were alive at the time of the discharge

adult heart lung recipients induction immunosuppression transplants january 2000 december 2009

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2009)

2011

Analysis is limited to patients who were alive at the time of the discharge

adult heart lung recipients induction immunosuppression transplants january 2000 december 20091

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTSInduction Immunosuppression (Transplants: January 2000 - December 2009)

Any Induction Polyclonal ALG/ATG OKT3 IL-2R Antagonist

2011

Analysis is limited to patients who were alive at the time of the discharge

slide27

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression at Time of Follow-upFor follow-ups between January 2001 through June 2010

NOTE: Different patients are analyzed in Year 1 and Year 5

2011

Analysis is limited to patients who were alive at the time of the follow-up

slide28

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG RECIPIENTSMaintenance Immunosuppression Drug Combinations at Time of Follow-upFor follow-ups between January 2001 through June 2010

NOTE: Different patients are analyzed in Year 1 and Year 5

2011

Analysis is limited to patients who were alive at the time of the follow-up

slide29

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 1 Year Post-Transplant (Follow-ups: April 1994 - June 2010)

2011

slide30

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

POST-HEART-LUNG TRANSPLANT MORBIDITY FOR ADULTSCumulative Prevalence in Survivors within 5 Years Post-Transplant (Follow-ups: April 1994 - June 2010)

2011

slide31

Freedom from Coronary Artery Vasculopathy and Bronchiolitis Obliterans SyndromeFor Adult Heart-Lung Recipients (Follow-ups: April 1994-June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

2011

slide32
Freedom from Coronary Artery Vasculopathy For Adult Heart-Lung Recipients By Diagnosis Type (Follow-ups: April 1994-June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

P-value comparing all = 0.4542

2011

slide33
Freedom from Bronchiolitis Obliterans SyndromeFor Adult Heart-Lung Recipients By Diagnosis Type (Follow-ups: April 1994-June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

P-value comparing all = 0.7620

2011

slide34

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

Freedom from Severe Renal Dysfunction*For Adult Heart-Lung Recipients (Follow-ups: April 1994-June 2010)

2011

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ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

MALIGNANCY POST-HEART-LUNG TRANSPLANT FOR ADULTSCumulative Prevalence in Survivors(Follow-ups: April 1994-June 2010)

* Recipients may have experienced more than one type of malignancy so sum of individual malignancy types may be greater than total number with malignancy.

2011

freedom from malignancy for adult heart lung recipients follow ups april 1994 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

Freedom from MalignancyFor Adult Heart-Lung Recipients(Follow-ups: April 1994- June 2010)

2011

adult heart lung transplant recipients cause of death deaths january 1992 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2010)

2011

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ADULT HEART-LUNG TRANSPLANT RECIPIENTS: Relative Incidence of Leading Causes of Death(Deaths: January 1992 - June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

2011

heart lung transplantation2

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

HEART-LUNG TRANSPLANTATION

Pediatric Recipients

2011

age distribution of pediatric heart lung recipients transplants january 1982 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

AGE DISTRIBUTION OF PEDIATRIC HEART-LUNGRECIPIENTS (Transplants: January 1982 - June 2010)

2011

age distribution for donors of pediatric heart lung recipients transplants january 1982 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

AGE DISTRIBUTION FOR DONORS OF PEDIATRIC HEART-LUNG RECIPIENTS(Transplants: January 1982 - June 2010)

2011

age distribution of pediatric heart lung recipients by year of transplant

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Year of Transplant

Number of Transplants

NOTE: This figure includes only the heart-lung transplants that are reported to the ISHLT Transplant Registry. As such, this should not be construed as evidence that the number of pediatric heart-lung transplants worldwide has declined in recent years.

2011

age distribution of pediatric heart lung recipients by era of transplant

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

AGE DISTRIBUTION OF PEDIATRIC HEART-LUNG RECIPIENTSBy Era of Transplant

Percentage of Transplants

2011

number of centers reporting pediatric heart lung transplants

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTS

NEED TO UPDATE

2011

number of centers reporting pediatric heart lung transplants stratified by center volume

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

NUMBER OF CENTERS REPORTING PEDIATRIC HEART-LUNG TRANSPLANTSStratified by center volume

2011

diagnosis in pediatric heart lung transplant recipients transplants 1986 2009

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

“Other” includes Bronchiectasis, Alpha-1, and OB (non-ReTX)

DIAGNOSIS IN PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS (Transplants: 1986-2009)

NOTE: Unknown diagnoses were excluded from this tabulation.

2011

slide47

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTS:AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2010

2011

slide48

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTS:DIAGNOSIS DISTRIBUTION BY LOCATION Transplants between January 2000 and June 2010

2011

slide49

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTS:DONOR AGE DISTRIBUTION BY LOCATIONTransplants between January 2000 and June 2010

2011

slide50

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival By Diagnosis(Transplants: January 1990 – June 2009)

2011

pediatric heart lung transplantation kaplan meier survival transplants january 1982 june 2009

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTATIONKaplan-Meier Survival(Transplants: January 1982 - June 2009)

2011

slide52

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTATION Kaplan-Meier Survival by Era (Transplants: January 1982 - June 2009)

2011

slide53

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANTATION Kaplan-Meier Survival by Era (Transplants: January 1982 - June 2009)Conditional on Survival to 1 Year

2011

pediatric heart lung transplant recipients cause of death deaths january 1992 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: January 1992 - June 2010)

2011

pediatric heart lung transplant recipients cause of death deaths april 1994 june 2010

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS: Cause of Death(Deaths: April 1994 - June 2010)

2011

slide56
PEDIATRIC HEART-LUNG TRANSPLANT RECIPIENTS: Relative Incidence of Leading Causes of Death(Deaths: April 1994 - June 2010)

ISHLT

ISHLT

J Heart Lung Transplant. 2011 Oct; 30 (10): 1071-1132

2011