Discovery of DNA. Friedrich Meischer in 1869. Discovery of the structure of DNA. Composition. What are the components? What is a base? What is a nucleo s ide? What is a nucleo t ide? What are the bases? What is the sugar? What is phosphate?. OK… what did they know. Composition
Friedrich Meischer in 1869
Let’s look at each of these circumstances…..
So, it was not obvious…
And who was Jerry
Donohue and why
was he important?
You need the structure on the left.
Watson and Crick originally worked with the structure on the right.
That hydrogen bonds were important in the structure of DNA was known before Watson (James Dewey Watson) and Crick (Francis Harry Compton Crick) initiated their “MODEL BUILDING”
Watson and Crick then indirectly obtained a prepublication version of Franklin's DNA X-ray diffraction data possibly without her knowledge, and a prepublication manuscript by Pauling and Corey, giving them critical insights into the DNA structure
A Nobel Prize is either given entirely to one person, divided equally between two persons, or shared by three persons.
3 x 109 x 0.34 nm x 2 = 20.4 x 108 nm
1 meter = 1 meter
1012 meters = 1 terameter
109 meters = 1 gigameter
106 meters = 1 megameter
103 meters = 1 kilometer
100 meters = 1 meter
10-3 meters = 1 millimeter
10-6 meters = 1 micrometer
10-9 meters = 1 nanometer
10-12 meters = 1 picometer