HIV. Characteristics of the virus. Characteristics of the virus. Icosahedra (20 sided), enveloped virus of the lentivirus subfamily of retroviruses. Two viral strands of RNA found in core surrounded by protein outer coat.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Sexual Blood products
Mother-to-child Multiple infection
Ann. Intern. Med.137 (5 Pt 2): 381–433. PMID12617573
Antiretroviral (ARV) drugs are broadly classified by the phase of the retrovirus life-cycle that the drug inhibits.
RTIs come in three forms:
World Health Organization. March 2005. Retrieved 2006-03-12
Emau P, Jiang Y, Agy MB, et al. (2006).
Ren J, Bird LE, Chamberlain PP, et al. (2002). "Structure of HIV-2 reverse transcriptase at 2.35-A resolution and the mechanism of resistance to non-nucleoside inhibitors". Proc Natl Acad Sci USA99 (22): 14410–15. doi:10.1073/pnas.222366699. PMID12386343
Rang, H. P., Dale, M. M., Ritter, J. M., & Flower, R. J. (2007). Rang and Dale's Pharmacology (6th Edition ed.). Philadelphia: Churchill Livingstone Elsevier.
FortovaseTM (saquinavir) soft gelatin capsules. Product information (November 1997)
Steigbigel RT, Cooper DA, Kumar PN, et al. (July 2008).
Savarino A (December 2006). "A historical sketch of the discovery and development of HIV-1 integrase inhibitors". Expert Opin Investig Drugs15 (12): 1507–22.
An HIV virion binds to a CD4+ human cell. The two bottom pictures depict two proposed models of HIV fusion with the cell.
Biswas P, Tambussi G, Lazzarin A (2007). "Access denied? The status of co-receptor inhibition to counter HIV entry" (abstract page). Expert Opin Pharmacother8 (7): 923–33. doi:10.1517/14656518.104.22.1683. PMID17472538
Levy JA (January 2009). "HIV pathogenesis: 25 years of progress and persistent challenges". AIDS23 (2): 147–60. doi:10.1097/QAD.0b013e3283217f9f. PMID19098484
Liu YJ (2005). "IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors". Annu Rev Immunol23: 275–306.
5 pills, BID
3 pills, BID
3 pills, QD
2 pills, QD
The Move Toward Lower Pill Burdens
Daily pill burden
10 pills, Q8H
Thakur, D. S. et al. “Anti-HIV Agents: A Step Toward Future” International Journal of Pharmaceutical Sciences Review and Research (2010) Vol. 3, pp. 10-18.