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Biostatistics


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    1. Biostatistics • Statistics is the collection, processing, interpretation and presentation of numerical information. Biostatistics is the application of statistics to questions about human health. Because the factors that affect human health are various, biostatistics is an umbrella term that encompasses statistical research in several subject matter areas. These areas include pharmacology, medicine, biotechnology, biology, genetics, and public health.

    2. Science • Systematized knowledge derived from observation, study and experimentation carried on in order to determine the nature or principles of what is being studied.

    3. Undergraduate Preparation • Math 150,151,250 Calculus I,II,III • Math 300 Discrete Mathematics • Math 240 Linear Algebra • Math 452 Computational Bioinformatics • Math 429 Operations Research • Math 352 Probability and Statistics • Math 350 Differential Equations and Dynamical Systems • Comp 420 Database Theory and Design • Comp 262 Computer Organization and Architecture • Comp 345 Digital Image Processing • Comp 445 Image Analysis and Pattern Recognition • Biol 431 Bioinformatics • Phys 434 Biomedical Imaging

    4. Degree Program Courses • 110-A,B Basic Biostatistics • 115 Topics in Estimation • 200-A,B,C Biostatistics • 201 Applied Regression • 202 Theory of Regression Analysis • 206-A,B,C StatisticsinPsychiatricandBiobehavioralResearch • 209 Statistical Modeling in Epidemiology • 210 Statistical Methods for Categorical Data • 212 Distribution Free Methods • 213 Statistical Simulation Techniques • 215 Survival Analysis • 220 Experimental Statistics • 234 Applied Bayesian Inference • 250-A,B LinearStatisticalModels. • 251MultivariateBiostatistics • 403-A Computer Management of Health Data

    5. Graduate Programs in Biostatistics • · University of California, Los Angeles Department of Biostatistics - Los Angeles, • California • · University of California at Berkeley School of Public Health Inter-Departmental • Group in Biostatistics - Berkeley, California • · Harvard School of Public Health Department of Biostatistics - Boston, • Massachusetts • · Johns Hopkins University School of Hygiene and Public Health Department of • Biostatistics - Baltimore, Maryland • · University of Michigan at Ann Arbor School of Public Health Department of • Biostatistics - Ann Arbor, Michigan • · University of Minnesota at Twin Cities Division of Biostatistics - Minneapolis, • Minnesota • · University of North Carolina at Chapel Hill School of Public Health Department • of Biostatistics - Chapel Hill, North Carolina • (has the only undergraduate program in biostatistics) • · University of Washington at Seattle School of Public Health Department of • Biostatistics - Seattle, Washington • · Boston University School of Public Health Department of Biostatistics - Boston, • Massachusetts • · University of California, Davis Graduate Group in Biostatistics, Department of • Statistics - Davis, California

    6. Pharmaceutical/Biotechnology • Glaxo Wellcome • Pfizer • Merck • Bristol-Myers Squibb • Warner Lambert • Schering-Plough • Abbott Laboratories • Johnson & Johnson • Eli Lilly and Company • Roche • Pharmacia & Upjohn • Genentech • Amgen • Baxter Healthcare • SRI International • MicroTherapeutics

    7. Food and Drug Administration (FDA) • Center for Biologics Evaluation and Research (CBER) • Center for Devices and Radiological Health (CDRH) • Center for Drug Evaluation and Research (CDER) • Center for Food Safety and Applied Nutrition (CFSAN) • Center for Veterinary Medicine (CVM) • National Center for Toxicological Research (NCTR) • Office of the Commissioner (OC) • Office of Regulatory Affairs (ORA)

    8. National Institutes • National Cancer Institute NCI • National Eye Institute NEI • National Heart, Lung, and Blood Institute, NHLBI • National Human Genome Research Institute NHGRI • National Institute on Aging NIA • National Institute on Alcohol Abuse and Alcoholism NIAAA • National Institute of Allergy and Infectious Diseases NIAID • National Institute of Arthritis and Musculoskeletal and Skin Diseases NIAMS • National Institute of Biomedical Imaging and Bioengineering NIBIB • National Institute of Child Health and Human Development NICHD • National Institute on Deafness and Other Communication Disorders NIDCD • National Institute of Dental and Craniofacial Research NIDCR

    9. National Institutes(cont.) • National Institute of Diabetes and Digestive and Kidney Diseases NIDDKD • National Institute of Drug Abuse NIDA • National Institute of Environmental Health Sciences NIEHS • National Institute of General Medical Sciences NIGMS • National Institute of Mental Health • National Institute of Neurological Disorders and Stroke NINDS • National Institute of Nursing Research NINR • National Library of Medicine NLM • Centers • National Center for Information Technology CIT • National Center for Scientific Review CSR • National Center for Complementary and Alternative Medicine NCCAM • National Center for Minority Health and Health Disparities NCMHD • National Center for Research Resources NCRR • National Institute of Health Clinical Center CC

    10. CDC Organization • Coordinating Center for Environmental Health and Injury Prevention • National Center for Environmental Health/ Agency for Toxic Substances and Disease Registry* (NCEH-ATSDR) provides national leadership in preventing and controlling disease and death resulting from the interactions between people and their environment • National Center for Injury Prevention and Control (NCIPC) prevents death and disability from non occupational injuries, including those that are unintentional and those that result from violence. • Coordinating Center for Health Information and Services • National Center for Health Statistics (NCHS) provides statistical information that guides actions and policies to improve the health of the American people. • National Center for Public Health Informatics (NCPHI) provides national leadership in the application of information technology in the pursuit of public health. • National Center for Health Marketing (NCHM) provides national leadership in health marketing science and in its application to impact public health. • Coordinating Center for Health Promotion • National Center on Birth Defects and Developmental Disabilities (NCBDDD) provides national leadership for preventing birth defects and developmental disabilities and for improving the health and wellness of people with disabilities. • National Center for Chronic Disease Prevention and Health Promotion (NCCDPHP) prevents premature death and disability from chronic diseases and promotes healthy personal behaviors. • Office of Genomics and Disease Prevention provides national leadership in fostering understanding of human genomic discoveries and how they can be used to improve health and prevent disease. • Coordinating Center for Infectious Diseases • National Center for Infectious Diseases (NCID) prevents illness, disability, and death caused by infectious diseases in the United States and around the world. • National Immunization Program (NIP) prevents disease, disability, and death from vaccine-preventable diseases in children and adults. • National Center for HIV, STD, and TB Prevention (NCHSTP) provides national leadership in preventing and controlling human immunodeficiency virus infection, sexually transmitted diseases, and tuberculosis. • Coordinating Office for Global Health provides national leadership, coordination, and support for CDC’s global health activities in collaboration with CDC’s global health partners • Coordinating Office for Terrorism Preparedness & Emergency Response provides strategic direction for the Agency to support terrorism preparedness and emergency response efforts. • National Institute for Occupational Safety and Health (NIOSH) ensures safety and health for all people in the workplace through research and prevention.

    11. Information and Quantitative Sciences in Health Care • · American Public Health Association (APHA) • · American Medical Informatics Association (AMIA) • · Society for Medical Decision Making (SMDM) • · AcademyHealth (health services and health policy research) • · Institute for Operations Research and the Management • Sciences (INFORMS) • · National Academy of Sciences (NAS) • Statistics and the Environment • · International Environmetric Society • · Society for Risk Analysis (SRA) • . National Oceanic and Atmospheric Administration

    12. Health Services Research • IMS Health • The Rand Corp. • Research in the Health Sciences • Fred Hutchinson Cancer Research Center • Mayo Clinic • St. Jude's Children's Research Hospital • CSCC (Collaborative Studies Coordinating Center); Chapel Hill, NC • Cleveland Clinic Foundation • Dana-Farber Cancer Institute • Memorial Sloan-Kettering Cancer Center • North Carolina State University • NISS (National Institute of Statistical Sciences) • University of Rochester • University of California, Los Angeles (Department of Health Services) • ISDS (Institute of Statistics and Decision Sciences) Duke University • University of Minnesota Cancer Center • National Committee for Quality Assurance (NCQA)

    13. Military Medical Research • U.S. Army Medical Department (AMEDD) Fort Sam Houston, TX • Fort Detrick, MD • U.S. Army Medical Research and Material Command (USAMRMC) • Congressional Research Programs • Congressional Special Interest Medical Programs (CSI) • Telemedicine and Advanced Technology Research Center (TATRC) • Congressionally Directed Medical Research Programs (CDMRP) • Breast Cancer, Prostate Cancer, Gulf War Illness • Madigan Army Medical Center , WA

    14. Contract Research • Quintiles • Covance • RTI (Research Triangle Institute) • PPD Pharmaco • Premier Research • Rho, Inc. • IBAH • ParExel • PRA International, Inc. • Software Development • SAS Institute • MathSoft - S Plus • SPSS • Consulting Firms • MedFocus • Trilogy Consulting • Smith Hanley Associates • Statistics and Biostatistics Division • The Cambridge Group, Ltd. • Pharmaceutical Division

    15. Professional Associations • Biostatistics-specific • · American Statistical Association (ASA) • · International Biometric Society (IBS) • · ENAR (IBS- East North American Region) • · WNAR (IBS- West North American Region) • · International Society for Clinical Biostatistics (ISCB) • · The Society for Clinical Trials (SCT) • Statistics, in general • · Institute of Mathematical Statistics • · The Bernoulli Society for Mathematical Statistics and Probability • · Society for Industrial and Applied Mathematics (SIAM) • · International Society for Bayesian Analysis (ISBA) • · International Statistical Institute (ISI) • · International Association For Statistical Computing