Drug Abuse. Self administration of drug or drugs in manner not in accord with accepted medical or social patterns. Drug Abuse. Psychological Dependenc (Habituation) addiction. Drug necessary to maintain user’s sense of well-being Physical Dependence, dependence
Self administration of drug or drugs in manner not in accord with accepted medical or social patterns
Compulsive, relapsing drug use despite negative consequences, at times triggered by cravings.
γ-hydroxybutyric acid (GHB)
Opiates are drugs that are derived from the Poppy Plant and are Central Nervous System (CNS) depressants.
Resembles Severe Influenza
Endogenous cannabinoids (Anandamide)
Act on CB1 receptors, presynaptically and inhibit the release of glutammateor GABA
Leading to disinhibition of dopamine neurons.
Onset of effects: within minutes
Effects: Euphoria, relaxation, visual distortions, drowsiness, diminished coordination and memory impairment.
used to treat depression
Block of dopamine transporter, by increasing conc in nucleus accumbens
Increased risk of intracranial haemorrhage, ischemic stroke, myocardial infarction and seizures.