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This study explores how gene polymorphisms affect protein activity and clinical response to immunosuppressive drugs in solid organ transplantation. Understanding these genetic variations can help optimize treatment strategies for transplant recipients.
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Table 1 Gene polymorphisms and their effect on protein activity and clinical response van Gelder, T. et al. (2014) Pharmacogenetics and immunosuppressive drugs in solid organ transplantation Nat. Rev. Nephrol. doi:10.1038/nrneph.2014.172