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Transplantation and Rejection

Transplantation and Rejection. Huan-Yao Lei, Ph.D. Department of Microbiology & Immunology College of Medicine National Cheng Kung University. Summary of Chapter 21 Transplantation and rejection. Transplantation is the form of treatment. The barrier to transplantation

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Transplantation and Rejection

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  1. Transplantation and Rejection Huan-Yao Lei, Ph.D. Department of Microbiology & Immunology College of Medicine National Cheng Kung University

  2. Summary of Chapter 21 Transplantation and rejection • Transplantation is the form of treatment. • The barrier to transplantation • The immune response in transplantation depends on a variety of factors. • Rejection results from a variety of different immune effector mechanisms. • HLA matching is one of two major methods for preventing rejection of allografts. • Successful organ transplantation depends on the use of immunosuppressive drugs. • The ultimate goal in transplantation is to induce donor-specific tolerance. • Shortage of donor organs and chronic rejection limit the success of transplantation.

  3. Immunity to Cancers Huan-Yao Lei, Ph.D. Department of Microbiology & Immunology College of Medicine National Cheng Kung University

  4. Summary of Chapter 22 Immunity to cancers • Can the immune system protect the host from cancer? • Tumors can induce immunity. • Tumor antigens have been characterized by three means - immunization-challenge experiments, T cell reactivity, and antibody reactivity. • Vigorous anti-tumor immune responses are compromised by regulatory mechanisms. • Three major categories of experimental immunotherapy are used for human cancer.

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