ExposureRoutes/ Infectious Disease Epidemiology. ENV H 451/541c. John Scott Meschke Office: Suite 2338, 4225 Roosevelt Phone: 206-221-5470 Email: [email protected] Today’s Objectives. Recognize the various routes of exposure and portals of Entry/Exit
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Sources, Reservoirs, Transport and Persistence (in the Environment)
Ability to Enter a Portal in the Human or Other Host
Ability to Reach and Proliferate at Site(s) of Infection in the Host
Excretion of the Agent from the Host
Quantity and "Quality" (including virulence) of the Infectious
THE PROCESS OF INFECTION Host Susceptibility
Localized Infections Host Susceptibility
Generalized Infections Host Susceptibility
Microbes differ in their ability to produce the different outcomes of infection:
Epidemiology includes: Host Susceptibility
A disease or condition at involves many or an excessive number of people at the same time and the same place
The occurrence of a disease or condition at a frequency that is unusual or unexpected
increase above background or endemic level
What Are Relative Risks for Each Food Item???
What is Odds Ratio???
OR = (a/c)/(b/d) = ad/bc