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Sex-Linked Genetics. What are sex chromosomes? X and Y Which sex chromosome is home of most sex-linked traits? X (much larger). Karyotypes: Is this a male or female?. Male. What are examples of traits that are sex-linked?. What are examples of traits that are sex-linked?

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sex linked genetics
Sex-Linked Genetics

What are sex chromosomes? X and Y

Which sex chromosome is home of most sex-linked traits? X (much larger)

what are examples of traits that are sex linked
What are examples of traits that are sex-linked?

What are examples of traits that are sex-linked?

1)Color blindness – (red-green)

2) Hemophilia

3) Muscular Dystrophy

4) Male pattern baldness

All are on the X-chromosome

should see
Should See

Circle, Square, star,

should see7
Should see

Square, circle

should have seen
Should have seen

Faint Brown boat, colorblind individuals would have seen nothing.

should see12
Should see

Colorblind individuals should see a yellow square.

Normal sight should see circle and square.

ishihara test
Ishihara Test

http://www.toledo-bend.com/colorblind/Ishihara.html

hemophilia blood doesn t clot
Hemophilia – blood doesn’t clot

Czar Nicholas II of Russia and his family, photographed c. 1916, showing his wife Alexandra (who was a carrier of hemophilia), his four daughters, and (in the foreground) his son Alexis, perhaps the most famous European royal with hemophilia. http://www.humanillnesses.com/original/Gas-Hep/Hemophilia.html

muscular dystrophy
Muscular Dystrophy

Muscles form incorrectly, including heart and lungs

 death by early 30’s

male pattern baldness
Male Pattern Baldness

Some evidence hints at X linked status

Androgens (male sex hormones) play a key role in balding--castrated men don't go bald--and the AR gene helps them do their work. The researchers found the balding men were much more likely to have a particular version of the AR gene than the non-balding men, which they took to mean they'd found a genetic variant that triggers baldness.

http://www.straightdope.com/columns/050819.html

assign letters to each disorder
Assign letters to each disorder

Colorblindness

B = normal b = colorblind

Hemophilia

H = normal h = hemophilia

Muscular Dystrophy

M = normal m = muscular dystrophy

Male pattern baldness

P = normal p = male pat. baldness

fill in this table of phenotypes with the correct genotype
Fill in this table of phenotypes with the correct genotype

XBXB

XBY

m.d. female

XhY

Normal (Carrier) female

slide19

Fill in this table of phenotypes with the correct genotype

XBXB

XBY

Female with M.D.

XhY

Normal, carrier female

a normal man and a woman with hemophilia plan on having a baby
A normal man and a woman with hemophilia plan on having a baby.

1. Dom = normal Rec= hemophilia

2. H = normal h = hemophilia

3.Mom= XhXh Dad= XHY

4.

  • 5/6.
  • Chance of normal = 2/4
  • Chance of Carrier = 2/4
  • Chance of hemo. = 2/4

Xh

Xh

XH

Y