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Histology Laboratories Molecules to Systems 2003 Compiled by James D. Jamieson, MD/PhD

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Histology Laboratories Molecules to Systems 2003 Compiled by James D. Jamieson, MD/PhD Thomas L. Lentz, MD. No part of this image collection may be distributed outside of the Yale University Intranet. Acknowledgements. Sources of Micrographs, Diagrams and Figures.

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slide1
Histology Laboratories

Molecules to Systems

2003

Compiled by

James D. Jamieson, MD/PhD

Thomas L. Lentz, MD

No part of this image collection may be distributed outside of the Yale University Intranet.

acknowledgements
Acknowledgements

Sources of Micrographs, Diagrams and Figures

Alberts, B. et al. Molecular Biology of the Cell. 4th Edition, Garland Science, New York, 2002.

Gartner, L. P. and Hiatt, J. L. Color Atlas of Histology, Williams & Wilkins, Baltimore, 1994.

Kerr, J. B. Atlas of Functional Histology. Mosby, London, 1999.

Kessel, R. G. and Kardon, R. H. Tissues and Organs: a text-atlas of scanning electron microscopy. W. H. Freeman, San Francisco, 1979.

Lentz, T. L. Cell Fine Structure. W. B. Saunders, Philadelphia, 1971.

Lodish, H. et al. Molecular Cell Biology. W. H. Freeman, New York, 2000.

Mizoguti, H. Color Slide Atlas of Histology. Nihon Shashin Shinbunsha, Tokyo.

Young, B. and Heath, J. W. Wheater’s Functional Histology. Churchill Livingstone, Edinburgh, 2000.

Micrographs taken by George Palade, Marilyn Farquhar, James D. Jamieson, Nicolai Simionescu, Maya Simionescu, David Castle, Thomas L. Lentz.

Web Resources

http://info.med.yale.edu/webpath/webpath.htm

Cushing Library Educational Software/Cell Biology/Several Histology Resources

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Germinal Center (GC)

Peyer’s Patches (Lymphoid Follicles) in Small Gut

slide10
Diffuse GALT in gut lamina propria

Organized GALT/MALT

GALT: gut-associated lymphoid tissue

MALT: mucosa-associated lymphoid tissue

slide11
Lymphoid follicle

Germinal center

Peyer’s Patch

slide12
Afferent lymphatic

Subcapsular sinus

Cortex

Efferent lymphatics

Medullary cords

Hilus

Medulla

Lymph Node

Secondary follicles

slide13
Cortex

Medulla

Germinal centers

Lymph Node

slide15
Germinal center: B cell proliferation and maturation

Mantle of resting and memory B cells

Secondary Follicle

slide20
Cortex

Medulla

Thymus

slide26
White pulp

Red pulp

PALS

Trabeular artery

Spleen

slide27
B cell mantle

GC

Central arteriole

PALS (T cells)

Spleen

slide28
Venous sinus

Endothelial cells

Spleen Red Pulp

slide33
Benign Reactive Lymph Node

Which cells are responding?

slide34
Adenocarcinoma Metastases to Lymph Node

How did the tumor cells get to this location?

slide35
Adenocarcinoma Metastases to Lymph Node

How did the tumor cells get to this location?

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