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Clopidogrel Stratification in TIMI Risk Score for Cardiovascular Outcomes

Study results show significant risk reduction with Clopidogrel in different TIMI risk score strata for cardiac mortality, MI, or stroke compared to placebo. Stratifying by TIMI risk score can guide treatment decisions.

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Clopidogrel Stratification in TIMI Risk Score for Cardiovascular Outcomes

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  1. CURE: Primary Outcome Stratified by TIMI Risk Score p = 0.004 p = 0.03 p = 0.04 RR 0.73 (0.60-0.90) RR 0.85 (0.74-0.98) RR 0.71 (0.52-0.97) 20.7% 15.9% Cardiac Mortality, MI or Stroke (%) 11.4% 9.8% 5.7% 4.1% Clopidogrel Placebo Placebo Clopidogrel Placebo Clopidogrel Low Risk TRS 0-2 Intermediate Risk TRS 3-4 High Risk TRS >5

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