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OPTIMIZE-HF

OPTIMIZE-HF. Three strategies for using brain- natriuretic -peptide (BNP) levels to predict one-year outcomes. Entrance BNP. Discharge BNP. Ratio Entrance BNP : Discharge BNP. Addition of discharge BNP to risk prediction led to risk reclassification:

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OPTIMIZE-HF

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  1. OPTIMIZE-HF • Three strategies for using brain-natriuretic-peptide (BNP) levels to predict one-year outcomes. Entrance BNP Discharge BNP RatioEntrance BNP : Discharge BNP • Addition of discharge BNP to risk prediction led to risk reclassification: • 15.6% who were clinically high risk → nearly all reclassified to intermediate risk. • 37% at clinically intermediate risk → reclassified over half to low risk and the rest to high-risk status. • 12.3% at clinically low risk → all reclassified to intermediate risk. ER ER ER ER BNP BNP BNP BNP • Discharge BNP Model The most robust and the best discrimination for one-year mortality. Felker GM. Heart Failure Society of America 2010 Scientific Meeting; September 14, 2010; San Diego, CA. Abstract 19.

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