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R etrolental Fibroplasia. Retinopathy of Prematurity Disturbance in the retinal vascularization in premature infants May be acute or chronic Usually bilateral, often asymmetric Causative role of supplemental oxygen. R etrolental Fibroplasia. Major risk factors Decreasing gestational age

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r etrolental fibroplasia
RetrolentalFibroplasia
  • Retinopathy of Prematurity
  • Disturbance in the retinal vascularization in premature infants
  • May be acute or chronic
  • Usually bilateral, often asymmetric
  • Causative role of supplemental oxygen
r etrolental fibroplasia1
RetrolentalFibroplasia
  • Major risk factors
    • Decreasing gestational age
    • Decreasing birth weight
  • Other associated risk factors
    • Acidosis
    • Apnea
    • PDA
    • Septicemia
    • Blood transfusions
    • Intraventricularhemorrhage
retrolental fibroplasia clinical manifestations
RetrolentalFibroplasiaClinical Manifestations

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.

retrolental fibroplasia clinical findings
RetrolentalFibroplasiaClinical Findings

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.

slide6
Stage 1 ROP

Stage 2 ROP

Stage 3 ROP

slide7
Stage 4 ROP

Stage 5 ROP

retrolental fibroplasia diagnosis
RetrolentalFibroplasiaDiagnosis
  • Recommendations
    • Systematic serial ophthalmologic examinations of infants at risk
    • Infants weighing <1500g at birth
    • Infants born before 31 weeks AOG
    • Infants weighing >1500g at birth who have an unstable clinical course

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.

retrolental fibroplasia diagnosis1
RetrolentalFibroplasiaDiagnosis
  • Recommendations
    • Initial examination should be performed at 4th to 6th week of chronological age
    • ROP is diagnosed most often at 32nd to 44th week after conception.
    • Screening should continue until the retina is fully vascularized, until the changes of ROP have undergone spontaneous resolution, or until appropriate treatment has been given.

Reference: Nelson Textbook of Pediatrics. 18th Edition. 2007.

retrolental fibroplasia treatment
RetrolentalFibroplasiaTreatment
  • Early Treatment of Retinopathy of Prematurity Study
    • Recommends treatment for infants with Stage 2 disease with vascular tortuosity and engorgement
  • Laser – treatment modality of choice
  • Vitrectomy and lensectomy in cicatricial disease

References: Nelson Textbook of Pediatrics. 18th Edition. 2007. Vaughan & Asbury’s General Ophthalmology 17th Edition. 2008.

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