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Microbe of the Week - PowerPoint PPT Presentation


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Microbe of the Week. Salmonella typhi Gram-negative, motile, mesophilic enteric bacterium Causative agent of typhoid fever (aka “enteric fever”. Microbe of the Week. Salmonella typhi Gram-negative, motile, mesophilic enteric bacterium Causative agent of typhoid fever (aka “enteric fever”.

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slide1

Microbe of the Week

  • Salmonella typhi
    • Gram-negative, motile, mesophilic enteric bacterium
    • Causative agent of typhoid fever (aka “enteric fever”
slide2

Microbe of the Week

Salmonella typhi

Gram-negative, motile, mesophilic enteric bacterium

Causative agent of typhoid fever (aka “enteric fever”

slide3

Microbe of the Week

Salmonella typhi

Gram-negative, motile, mesophilic enteric bacterium

Causative agent of typhoid fever (aka “enteric fever”

slide4

Sources

  • Humans are sole reservoir (does not infect animals)
  • Carriers may harbor the organism in their gall bladder
  • Contaminated food – by handlers (milk, sandwiches, meat, cake!)
    • or …
  • Contaminated water – e.g. shellfish in polluted waters
  • Organism survives in shellfish up to 4 days, sea water up to 9 days, for weeks in sewage
  • Transmission: mainly from water contaminated with human waste or human carriers
slide5

Typhoid Mary

Sociological implications of infectious disease

  • Typhoid Mary's real name was Mary Mallon.
  • Irish immigrant who made her living as a cook
  • Mallon was the first person found to be a "healthy carrier" of typhoid fever in the United States.
    • She herself was not sick – but over 30% of the bacteria in her feces were S. typhi
  • Mallon is attributed with infecting 47 people with typhoid fever, three of whom died.
  • Interred on a N. Brother Island, NY for 26 years
    • 1907-1910
    • 1915- till her death in 1938
slide6

Typhoid Mary

Sociological implications of infectious disease

  • Typhoid Mary's real name was Mary Mallon.
  • Irish immigrant who made her living as a cook
  • Mallon was the first person found to be a "healthy carrier" of typhoid fever in the United States.
    • She herself was not sick – but over 30% of the bacteria in her feces were S. typhi
  • Mallon is attributed with infecting 47 people with typhoid fever, three of whom died.
  • Interred on a N. Brother Island, NY for 26 years
    • 1907-1910
    • 1915- till her death in 1938
slide7

Typhoid Mary

Sociological implications of infectious disease

  • Typhoid Mary's real name was Mary Mallon.
  • Irish immigrant who made her living as a cook
  • Mallon was the first person found to be a "healthy carrier" of typhoid fever in the United States.
    • She herself was not sick – but over 30% of the bacteria in her feces were S. typhi
  • Mallon is attributed with infecting 47 people with typhoid fever, three of whom died.
  • Interred on a N. Brother Island, NY for 26 years
    • 1907-1910
    • 1915- till her death in 1938