Catalytic antibodies. Classes of biological catalysts Enzymes, RNA and antibodies Antibodies are proteins (immunoglobulins) that circulate in the blood and function as defense against foreign molecules Antibodies form specific stable complexes with antigens ( anti body gen erators).
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Classes of biological catalysts
Structure of immunoglobulins
Structure and function of IgG
Binding energy provided by:
Generation of catalytic MABs Fig. 8.3
Design of transition state analog
Hapten-carrier protein conjugate
Phage display libraries Fig. 8.4
Phage selection Fig. 8.5
Transition state theory
Catalytic potential of antibodies
Application of antibodies