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Bio 342 Human Physiology. Pick up an information form, complete it, and turn it in before leaving. A physiologist asks…. How do things work in the human body? How is stability achieved? What are the causes and consequences of disruptions of stability? How can stability be restored?
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Bio 342Human Physiology • Pick up an information form, complete it, and turn it in before leaving.
A physiologist asks… • How do things work in the human body? • How is stability achieved? • What are the causes and consequences of disruptions of stability? • How can stability be restored? • How do we know what’s going on inside the body? • How have things come to be the way they are?
Theme of this course: Homeostasis
First Demonstration for Bio 342 Human Physiology • Listen carefully to the music and to how it is interpreted • Observe the human body in action during the performance of the piece • Consider the activity of cells, tissues, and organs in the musician
BIO 342 HUMAN PHYSIOLOGY • PHYSIOLOGY: The study of the function of cells, tissues, organs, and organ systems. • THE TEXT: Widmaier et al. 2008 (11th ed.) • Chapter 2-5 review of other courses • Using your textbook
General Course Objectives 1. To develop a basic understanding of the principles of physiology, with an emphasis on homeostatic mechanisms and negative feedback control. • 2. To develop an appreciation for the experimental basis of our knowledge of physiology. • 3. To sharpen laboratory skills with exercises that require forethought, planning, andrefinement.
General Course Objectives • 4. To organize and analyze information so as to develop critical thinking skills. • 5. To write concisely in the form of scientific abstracts. • 6. To communicate effectively in oral form.
The Syllabus (on the course websitehttp://webs.wofford.edu/davisgr/bio342/) • Office & home phone numbers • E-mail (davisgr@wofford.edu) • Lecture topics by week • Text chapters in parentheses • Read in advance of lectures
A Website for this Course! • Check daily. • Get Study Questions and Powerpoint files via the website.
LABORATORIES • 5-8 Computer setups, <22 persons per lab • 2:00 - 5:00 Mon (Davis) & Tues 8-11 • 2:30 – 5:30 Tue (Moeller) • 2:00 – 5:00 Wednesday (Nguyen) • 2:30 – 5:30 Thursday (Nguyen) • May shift topics due to availability of animals • 1 Lab Report in the form of abstracts • very concise, based on lab data • Incorporate statistics • With revision and resubmission • No separate lab tests; lecture tests include labs • This week’s Lab: Using live animals!
GRADING • 3 lecture tests = 60% • multiple choice (choose all correct answers) • Some short answer • Rarely fill in the blank • Sometime create or complete graph or diagram • discussion question(s) • Cumulative final exam = 20% • Other work = 20% • Abstract = 10% • 1 Question Quizzes (1QQs) = 10%
Honor Code • All worked is to be “pledged.” • Issues of plagiarism to be handled by the Honor Court
ODDS AND ENDS • NO FOOD or DRINKS in Lab • Possible limited lab swapping • under special circumstance • students arrange paired swap • prior approval • See “Attendance” webpage • BE ON TIME, READY TO GET TO WORK • DON’T ASK ABOUT LENGTH OF LAB • BE READY TO START ON TIME
Study Questions & Quizzes • Questions provided for each chapter (On the website!) • Read the book and answer the questions PRIOR to class meeting • Class time is used to deal with problematical topics and reinforce the major concepts • Be ready for 1QQs
Study Questions & Quizzes • Rationale for this format: • Writing helps to consolidate memory and recall • Greater effort results in better retention and understanding • Students are not passive learners • Able to cover more information • Improve MCAT, DCAT and GRE scores
More stuff • Be early or on time for lecture and lab • Pay attention (no cell phones, email, Facebook, etc. during lecture or lab)
Chapter 1 and parts of 16 • Tissues • Organs • Organ Systems • Homeostasis • Negative feedback • Two detailed examples: Thermoregulation and Glucose Homeostasis
Genetics & Development Cell & Molecular 200
Cell types • Neuron • Hepatocyte • Cardiac myofiber • Septal cell (lung) • Purkinje fiber (heart) • Melanocyte • Enteroendocrine cell • Simple cuboidal cell of the proximal renal tubule • Basal cell of stratum germinativum (skin) • Endothelial cell • Fibroblast • Osteocyte • Chondrocyte • Acinar cell of pancreas • Beta cell of Islet of Langerhans • Schwann cell
More cell types • Sertoli cell • Leydig cell • Hair cell (inner ear) • Smooth myofiber of arteriole • Mast cell • Unilocular adipocyte • Osteoblast • Monocyte • Langhan’s giant cell • Megakaryocyte • Satellite cell (ganglion) • Myofibroblast in capsule of spleen • Odontoblast • Ameloblast • Myoepithelial cell of salivary gland
Even More Cell Types • Parietal cell • Chief cell (stomach) • Paneth cell • Podocyte • Juxtaglomerular cell • Cell of the macula densa • Chromaffin cell (adrenal medulla) • Cell of the corona radiata • Spermatogonia • Granulosa lutein cell • Secretory cell of the zona glomerulosa • Secretory cell of the zonal fasciculata
Figure 01.01c Anatomy
The Human Body:A Society of Cells • Imagine you are a cell. Ask yourself: • How did I get here? • What do I do for myself? (What are my special characteristics and functions?) • What do I do for the person in whom I reside? (What are my contributions to the whole organism? To homeostasis?) • What do I need simply to survive? • What do the other cells provide for me that I cannot obtain alone? • What governs my actions? • How long will I live? • Can I be replaced? If so, how? • What would happen to the organism if I along with all the other cells of my type were to fail to function properly? Choose a cell type from list, have answers ready for class on Wednesday.
A physiologist asks… • How do things work in the human body? • How is stability achieved? • What are the causes and consequences of disruptions of stability? • How can stability be restored? • How do we know what’s going on inside the body? • How have things come to be the way they are?