Pharmaceutical Development. Training Workshop on Pharmaceutical Development with focus on Paediatric Formulations Protea Hotel Victoria Junction, Waterfront Cape Town, South Africa Date: 16 to 20 April 2007. Pharmaceutical Development. Pre-Formulation and Formulation Development
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Training Workshop on Pharmaceutical Development with focus on Paediatric Formulations
Victoria Junction, Waterfront
Cape Town, South Africa
Date: 16 to 20 April 2007
How is it achieved?..........
One option….Binary Mix Compatibility Testing:
(12). C. Ahlneck and G. Zografi, Int. J. Pharm., 62, (1990) 87.
(13). J.T. Carstensen and T. Morris, J. Pharm. Sci., 82 (1993) 657.
(14). J.I. Wells, Pharmaceutical Preformulation, Excipient Compatibility, Ellis Horwood, Chapter 8 (1987).
(24). J.C. Callahan, G.W. Cleary, M. Elefant, G. Kaplan T. Kensler and R.A.Nash, Drug Dev. Ind. Pharm., 8 (1982) 355.
Further theories of interaction:
(29). C. Ahlneck and P. Lundgren, Acta Pharm. Suec., 22 (1985) 305
* thioglycollic acid is an impurity of the organotin heat stabilising plastic additive (di-n-octyltin-bis [iso-octylthioglycollate]) in packaging material
(53). Sides et al, J. Pharm. Biomed. Anal., 25 (2001) 379-386