slide1 n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
The antibiotic market is a >$30 billion market worldwide PowerPoint Presentation
Download Presentation
The antibiotic market is a >$30 billion market worldwide

Loading in 2 Seconds...

play fullscreen
1 / 6

The antibiotic market is a >$30 billion market worldwide - PowerPoint PPT Presentation


  • 163 Views
  • Uploaded on

The antibiotic reality. The antibiotic market is a >$30 billion market worldwide The antibiotic pipeline is as empty as it has been since the discovery of antibiotics (97% of antibiotics in development are analogs of existing drugs) Antibiotic resistance has emerged as a major challenge

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'The antibiotic market is a >$30 billion market worldwide' - jafari


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
slide1

The antibiotic reality

The antibiotic market is a >$30 billion market worldwide

The antibiotic pipeline is as empty as it has been since

the discovery of antibiotics

(97% of antibiotics in development are analogs of existing drugs)

Antibiotic resistance has emerged as a major challenge

in public and personal health

The search for single “blockbuster” broad-spectrum

antibiotics is both medically and ecologically foolish

slide3

The new antibiotic landscape

  • The search for single “blockbuster” broad-spectrum antibiotics is medically, ecologically and financially untenable.
  • Origin is committed to the design of effective
  • narrow spectrum antimicrobials that:
  • Specifically target pathogenic organisms
  • Reduce the emergence of resistance
  • Leverage developments in diagnostics
  • and personalized medicine
bacteriocin diversity
Bacteriocin Diversity

Bacteriocins

May be universally

present in Bacteria,

certainly prevalent

E. coli - colicins

P. aeruginosa - pyocin

B. subtilis - subtilin

S. epidermis - epidermin

L. brevis - brevicin

Archaeacins

Universally present

pitted against microbial genes we have mainly our wits joshua lederberg
“…pitted against microbial genes we have mainly our wits.”Joshua Lederberg

Ia

E9

Our leads derive from a family of naturally-occurring antimicrobials, the bacteriocins

Ubiquitous

Specific and targetable

Nontoxic to vertebrates

Modifiable and patentable

slide6

3 billion years of R&D

Yr 0

Yr 7

Yr 15-20

For additional information, contact:

Dr. Robert Dorit or Dr. Margaret Riley

origin.antimicrobials@gmail.com

Post

Market

FDA

Discovery

Animal Trials

Phase II

Conventional antibiotics

Phase III

Preclinical

Phase I

Yr 0

Yr 2

Post

Market

FDA

Animal Trials

Phase II

Discovery

Phase III

Preclinical

Phase I

The lead to bedside pipeline